Intermittent fasting (IF) has gained increasing scientific and general attention. Most studied forms of IF include alternate-day fasting, modified alternate-day fasting, and time-restricted eating (TRE). Several cardiometabolic effects of IF have been described in animal models and, to a lesser extent, i...
ABSTRACT Objective This scoping review aimed to map evidence on açai supplementation combined with exercise in animal and/or human experimental studies. Methods The search considered six electronic databases and screening of relevant references. The selection process and data extraction were performed...
Troncoso, Mayarling Francisca;
Pavez, Mario;
Wilson, Carlos;
Lagos, Daniel;
Duran, Javier;
Ramos, Sebastián;
Barrientos, Genaro;
Silva, Patricio;
Llanos, Paola;
Basualto-Alarcón, Carla;
Westenbrink, B. Daan;
Lavandero, Sergio;
Estrada, Manuel.
BACKGROUND: Testosterone regulates nutrient and energy balance to maintain protein synthesis and metabolism in cardiomyocytes, but supraphysiological concentrations induce cardiac hypertrophy. Previously, we determined that testosterone increased glucose uptake—via AMP-activated protein kinase (AMPK)...
Louzada-Júnior, Adalberto;
da-Silva, Josimar Mota;
da-Silva, Vernon Furtado;
Castro, Antônio Clodoaldo Melo;
de-Freitas, Rodrigo Eufrásio;
Cavalcante, Joy Braga;
dos-Santos, Kennedy Maia;
Albuquerque, Ana Paula Azevedo;
Brandão, Paula Paraguassú;
Bello, Maria de Nazaré Dias;
Guimarães, Andrea Carmen;
Carvalho, Mauro Cesar Gurgel de Alencar;
Pernambuco, Carlos Soares;
Lima, Eder Benício Ramos;
Coelho, Renato Ramos;
Santos, César Augusto de Souza;
Bezerra, Jani Cleria Pereira;
Dantas, Estélio Henrique Martin;
Romeu-Silva, Paulo Martins;
da-Silva, Carolina Freitas;
Sampaio, Aristeia Nunes;
Valentim-Silva, João Rafael.
The exercise could play a central role to the fat management and glucose metabolism what can be a critical role in the health status of diabetic people, but the high intense exercise remains with controversial data about their effects. To identify the effect of the multimodal high-intensity interval trai...
Jiang, Su;
Zhao, Gaonian;
Lu, Jun;
Jiang, Min;
Wu, Zhenggang;
Huang, Yujing;
Huang, Jing;
Shi, Jinghua;
Jin, Jing;
Xu, Xinxuan;
Pu, Xuehua.
BACKGROUND: Circular RNA (circRNA) is highly expressed in the brain tissue, but its molecular mechanism in cerebral ischemia-reperfusion remains unclear. Here, we explored the role and underlying mechanisms of circRNA antisense non-coding RNA in the INK4 locus (circ_ANRIL) in oxygen-glucose deprivation a...
Hipoxia Encefálica/metabolismo,
MicroARNs/genética,
MicroARNs/fisiología,
Daño por Reperfusión/metabolismo,
ARN Circular,
Apoptosis,
Encéfalo,
Inhibidor p16 de la Quinasa Dependiente de Ciclina,
Células Endoteliales,
Glucosa/metabolismo,
Inflamación,
Oxígeno,
ARN Largo no Codificante
SUMMARY Type 2 diabetes mellitus is an important public health problem, with a significant impact on cardiovascular morbidity and mortality and an important risk factor for chronic kidney disease. Various hypoglycemic therapies have proved to be beneficial to clinical outcomes, while others have failed t...
Compuestos de Bencidrilo/uso terapéutico,
Canagliflozina/uso terapéutico,
Enfermedades Cardiovasculares/etiología,
Enfermedades Cardiovasculares/mortalidad,
Enfermedades Cardiovasculares/prevención & control,
Diabetes Mellitus Tipo 2/complicaciones,
Diabetes Mellitus Tipo 2/tratamiento farmacológico,
Nefropatías Diabéticas/etiología,
Nefropatías Diabéticas/metabolismo,
Nefropatías Diabéticas/prevención & control,
Tasa de Filtración Glomerular,
Glucosa/metabolismo,
Glucósidos/uso terapéutico,
Hipoglucemiantes/farmacología,
Hipoglucemiantes/uso terapéutico,
Riñón/efectos de los fármacos,
Riñón/metabolismo,
Riñón/fisiopatología,
Enfermedades Renales/etiología,
Enfermedades Renales/metabolismo,
Enfermedades Renales/prevención & control,
Transportador 2 de Sodio-Glucosa/farmacología,
Transportador 2 de Sodio-Glucosa/uso terapéutico,
Inhibidores del Cotransportador de Sodio-Glucosa 2/farmacología,
Inhibidores del Cotransportador de Sodio-Glucosa 2/uso terapéutico
Resumo Objetivo Analisar as alterações clínicas, metabólicas e sua relação com a resistência à insulina entre adolescentes. Métodos Estudo analítico, realizado com 357 adolescentes de escolas públicas estaduais de um município do Nordeste brasileiro. O formulário aplicado continha as vari...
Resistencia a la Insulina,
Métodos de Análisis de Laboratorio y de Campo,
Obesidad,
Estudios Epidemiológicos,
Antropometría,
Factores de Riesgo,
Estudios de Evaluación como Asunto,
Glucosa/metabolismo,
Metabolismo de los Lípidos,
Triglicéridos/metabolismo,
HDL-Colesterol/metabolismo,
Enfermedad Crónica
ABSTRACT GH is one of the insulin counterregulatory hormones which acts in the opposite way to insulin, increasing the glucose production by the liver and kidneys and decreasing glucose uptake from peripheral tissues, thus being a hyperglycemic hormone. When in excess, as in acromegaly, it induces glucos...
ABSTRACT Objective To test the influence of oral fructose and glucose dose-response solutions in blood glucose (BG), glucagon, triglycerides, uricaemia, and malondialdehyde in postprandial states in type 1 diabetes mellitus (T1DM) patients. Subjects and methods The study had a simple-blind, randomize...
Glucemia/análisis,
Glucemia/efectos de los fármacos,
Estudios Cruzados,
Diabetes Mellitus Tipo 1/metabolismo,
Relación Dosis-Respuesta a Droga,
Tolerancia a Medicamentos,
Fructosa/metabolismo,
Glucosa/metabolismo,
Periodo Posprandial/efectos de los fármacos,
Edulcorantes/metabolismo,
Triglicéridos/sangre
