Segundo o Ministério da Saúde, o número de casos notificados e confirmados de hepatite C no período entre 1999 e 2020 foi de 262.815
casos no Brasil. Em 2016, a OMS estabeleceu como objetivo global que as hepatites não fossem mais um problema de saúde pública em
2030. A partir de 2015, os agente...
ABSTRACT According to the World Health Organization, 71 million people live with chronic hepatitis C. The treatment of this disease requires assistance from specialized physicians and a highly complex health care system. The prison population has been recognized as being at a high risk of acquiring confi...
La infección por virus de la hepatitis C en pediatría se produce principalmente por transmisión vertical. La historia natural en niños consiste en alta tasa de eliminación espontánea, infección asintomática o cambios histológicos mínimos. Las complicaciones suelen observarse en la adolescencia ...
Abstract The clinical management of hepatitis C virus (HCV) infection presents several challenges today. WHO's goal is to eliminate it by 2030. It is an ambitious goal and difficult to meet given the barriers to care that arise. This is possible today thanks to the discovery of direct-acting antivirals (...
Resumen La principal infección viral transmisible por sangre es actualmente la debida al virus de hepatitis C (VHC). Uno de los mayores obstáculos para el logro de su control en la Argentina se relaciona con las dificultades de acceso al diagnóstico y tratamiento oportuno de las personas infectadas. E...
Abstract In addition to liver disease, the hepatitis C virus (HCV) has been associated with autoimmune phenomena, such as mixed cryoglobulin and glomerulonephritis (GN). Until recently, both chronic hepatitis and HCV extra-hepatic manifestations were treated with peg-interferon plus ribavirin, however th...
Lourenço, Mariana Sandoval;
Zitelli, Patricia Momoyo Y.;
Cunha-Silva, Marlone;
Oliveira, Arthur Ivan N.;
Lima, Roque Gabriel Rezende de;
Souza, Evandro de Oliveira;
Oliveira, Claudia P.;
Sevá-Pereira, Tiago;
Carrilho, Flair J.;
Pessoa, Mario G.;
Mazo, Daniel F..
OBJECTIVES: Despite higher rates of sustained virologic response (SVR), important concerns remain when patients with decompensated cirrhosis due to hepatitis C virus (HCV) are treated with direct-acting antiviral agents (DAA). Questions include efficacy, safety, and the magnitude of liver function improv...
ABSTRACT A retrospective cohort of 11,308 chronic hepatitis C infected patients treated with regimens that included Sofosbuvir (SOF), Daclatasvir (DCV), Simeprevir (SMV), or an association of Ombitasvir, Veruprevir/Ritonavir and Dasabuvir (3D) with or without Ribavirin (RBV) were assessed for sustained v...
Antivirales/uso terapéutico,
Brasil,
Quimioterapia Combinada,
Genotipo,
Hepacivirus/genética,
Hepatitis C/tratamiento farmacológico,
Hepatitis C Crónica/tratamiento farmacológico,
Persona de Mediana Edad,
Estudios Retrospectivos,
Ribavirina/uso terapéutico,
Resultado del Tratamiento
OBJECTIVES: The aim was to prospectively assess the variation in liver stiffness (LS) and the associated factors for LS progression in a cohort of naïve, non-responder (NR), and sustained virological response (SVR) chronic hepatitis C (CHC) patients. METHODS: This was a longitudinal study on CHC patien...
Antivirales/uso terapéutico,
Diabetes Mellitus,
Diagnóstico por Imagen de Elasticidad,
Hepatitis C Crónica,
Hepatitis C Crónica/tratamiento farmacológico,
Hepatitis C Crónica/patología,
Hígado/diagnóstico por imagen,
Hígado/patología,
Cirrosis Hepática/patología,
Estudios Longitudinales,
Hepatitis C Crónica/complicaciones
