Results: 50

High fat diet- induced obesity decreases ErbB receptors expression in liver and adipose tissue in C57BL/6 mice

Rev. chil. nutr; 51 (1), 2024
Neuregulins (NRGs) are a family of signaling proteins that bind to receptor tyrosine kinases of the ErbB family (ErbB2 to ErbB4), which can homo- or heterodimerize depending on their structural features and cell type. Many studies have proposed that decreased NRG levels are a common characteristic of obe...

Histomorphological, Histochemical and Ultrastructural Studies on the Healthy Liver of Yemen Veiled Chameleon (Chamaeleo calyptratus) in Southern Saudi Arabia

Int. j. morphol; 41 (5), 2023
SUMMARY: The livers of reptiles are being studied as a model for the link between the environment and hepatic tissue. There have been few investigations on the histology of reptile livers, and very few or no studies have examined the histology of liver of veiled chameleon (Chamaeleo calyptratus). This pa...

Efectos de fuentes de grasa sobre características del hígado y la morfometría intestinal en un modelo animal a temprana edad

RESUMEN El objetivo fue determinar el efecto del consumo de tres fuentes de ácidos grasos sobre el peso relativo, caracterización macroscópica y microscópica del hígado, y la morfometría intestinal en un modelo animal a temprana edad. Se utilizaron 76 pollitos distribuidos al azar, que recibieron u...

Diagnóstico y manejo de la colestasis intrahepática en el embarazo

La colestasis intrahepática del embarazo es producida por una disfunción de los hepatocitos, propia de la gestación. Las concentraciones elevadas de hormonas sexuales y la predisposición genética parecen ser factores importantes para su desarrollo. La incidencia depende de la composición étnica de...

Protective effect of linoleic acid on liver toxicity induced by methotrexate

Int. j. morphol; 41 (1), 2023
SUMMARY: We aimed to investigate the protective effect of linoleic acid on liver toxicity induced by methotrexate. The study was carried out in partnership with the Department of Anatomy and Department of Medical Pharmacology of Çukurova University Faculty of Medicine, using the laboratory facilities of...

Hepatoprotective and antioxidant effects of alcesefoliside from Astragalus monspessulanus

Abstract The hepatoprotective potential of alcesefoliside (AF) from Astragalus monspessulanus was investigated. Iron sulphate/ascorbic acid (Fe2+/AA) lipid peroxidation was induced in rat liver microsomes and pre-incubated with AF and silybin (100, 10 and 1 µmol). Pronounced effects were observed in 100...

Hígado y SARS-CoV-2: aspectos claves de la literatura

Resumen El nuevo coronavirus del síndrome respiratorio agudo grave de tipo 2 (SARS-CoV-2), virus que se ha expandido por todo el mundo, produce una infección respiratoria aguda capaz de producir la muerte; sin embargo, el daño en otros órganos también es frecuente. Diversos estudios han evidenciado ...

Efecto del extracto hidroalcohólico de la planta Lampaya medicinalis Phil. (Verbenaceae) sobre la esteatosis inducida in vitro en hepatocitos humanos

INTRODUCCIÓN: La enfermedad del hígado graso no alcohólico (EHGNA) es la forma más común de enfermedad hepática. A nivel celular se caracteriza por la acumulación de triglicéridos (TG) en forma de gotas lipídicas (GL) dando lugar a esteatosis e inflamación. Entre los factores relevantes para la...

Spontaneous and experimental poisoning by nitroxinil at 34% in goats

Pesqui. vet. bras; 41 (), 2021
This study describes the epidemiological, clinical, and pathological aspects of spontaneous and experimental poisoning by nitroxinil at 34% concentration in goats. The outbreak occurred on a farm in the municipality of Prata, Paraíba state. Nitroxinil was administered to a herd of 120 goats, of which 18...

Histomorphometric analysis of liver biopsies of treated patients with Gaucher disease type 1

Autops. Case Rep; 11 (), 2021
Gaucher disease (GD) is an autosomal recessive lysosomal disorder caused by a disturbance in the metabolism of glucocerebroside in the macrophages. Most of its manifestations - hepatosplenomegaly, anemia, thrombocytopenia, and bone pain - are amenable to a macrophage-target therapy such as enzyme replace...