Results: 4

The differences in homeostasis model assessment values in type 2 diabetic patients with different lengths of history of diabetes

ABSTRACT Objective Type 2 diabetes (T2DM) is characterized by the progressive deterioration of pancreatic islet β-cell function over time and insulin resistance. Knowing more about the differences in pancreatic islet function in T2DM patients who have had diabetes for different lengths of time can...

Duodenal-jejunal bypass normalizes pancreatic islet proliferation rate and function but not hepatic steatosis in hypothalamic obese rats

Braz. j. med. biol. res; 50 (5), 2017
Modifications in life-style and/or pharmacotherapies contribute to weight loss and ameliorate the metabolic profile of diet-induced obese humans and rodents. Since these strategies fail to treat hypothalamic obesity, we have assessed the possible mechanisms by which duodenal-jejunal bypass (DJB) surgery ...

Influência do binômio diabete e gravidez na atividade endócrina do pâncreas materno e fetal: estudo experimental em ratas

A gravidez é modelo natural de análise da reserva funcional do pâncreas materno. O pâncreas normal responde a este estímulo fisiológico com hiperatividade. Na falta de reserva funcional adequada, manifesta-se o diabete gestacional ou exacerba-se o diabete clínico. A glicose, elevada no meio intrau...