Results: 7

Papel de mediadores solúveis na resposta imune em modelos de proteção contra o mycobacterium tuberculosis

A imunoprofilaxia permanece como uma importante ferramenta para o controle da pandemia tuberculosa. Neste contexto, assume especial importância o estudo de marcadores que possam ser correlacionados à proteção contra a doença, tornando mais viável em termos de custo-benefício a avaliação de novas...

Glicoproteína P en leucocitos de sangre periférica de individuos sanos
Glycoprotein P in peripheral blood leukocytes of healthy individual

El objetivo de este trabajo fue estudiar la distribución de la expresión de la Gp-P y su ARNm en sangre periférica de una amplia población de sujetos sanos para identificar probables diferencias individuales. Para ello se estudiaron un total de 126 muestras sanguíneas mediantes inmunofluorescencia d...

Inhibition of vascular endothelial growth factor (VEGF) as a novel approach for cancer therapy

Medicina (B.Aires); 60 Suppl 2 (), 2000
Of the numerous growth factors and cytokines that have been shown to have angiogenic effects, vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF), appears to be a key factor in pathological situations which involve neovascularization as well as enhanced vascular pe...

La inflamación en la enfermedad de Alzheimer
Inflammation in Alzheimer's disease

Una serie de argumentos inducen a pensar que el fenómeno fisiopatológico inicial en la enfermedad de Alzheimer (EA) consiste en el depósito de BA4 globular originando las llamadas placas difusas. Sin embargo la mayoría de autores piensa que el solo depósito de amiloide globular no basta para explica...

Immunoregulation in human Schistosomiasis by idiotypic interactions and lymphokine-mediated mechanisms

Mem. Inst. Oswaldo Cruz; 82 (supl.4), 1987
Anti-idiotypic (anti-Id) T cells from schistosomiasis patients or former patients proliferate upon exposure to polyclonal or monoclonal anti-soluble egg antigen (SEA) antibodies. Chloroquine does not inhibit, the response, which is induced by F(ab')2 (but not soluble Fab) fragments of these antibodies. P...