Results: 8

Electrocardiographic effect of artemisinin-piperaquine, dihydroartemisinin-piperaquine, and artemether-lumefantrine treatment in falciparum malaria patients

Abstract INTRODUCTION: Artemisinin-based combination therapy (ACT), such as artemisinin-piperaquine (AP), dihydroartemisinin-piperaquine (DP), and artemether-lumefantrine (AL), is the first-line treatment for malaria in many malaria-endemic areas. However, we lack a detailed evaluation of the cardiotox...

Therapeutic failure after regimen with artemether-lumefantrine combination therapy: a report of three cases in Benin City, Nigeria

Abstract Artemisinin-based combination therapy (ACT) is recommended by the World Health Organization for the treatment of uncomplicated malaria. Currently, there appears to be a downward trend in the efficacy of ACT in some parts of sub-Saharan Africa because some patients have been positive for Plasmodi...

Effect of artemisinin-piperaquine treatment on the electrocardiogram of malaria patients

Abstract INTRODUCTION: Concern regarding the cardiotoxicity of antimalarials has been renewed because of their potential to cause QT/QTc interval prolongation related to torsade de pointes (TdP). Artemisinin-piperaquine (AP) is considered an effective artemisinin-based combination therapy (ACT) for mal...

Patient age does not affect mefloquine concentrations in erythrocytes and plasma during the acute phase of falciparum malaria

Braz. j. infect. dis; 20 (5), 2016
Abstract Objective To evaluate whether patient age has a significant impact on mefloquine concentrations in the plasma and erythrocytes over the course of treatment for uncomplicated falciparum malaria. Methods A total of 20 children aged between 8 and 11 years and 20 adult males aged between 22 and 41...

Malaria: tratamiento y quimioprofilaxis
Malaria: treatment and prophylaxis

Rev. chil. infectol; 17 (supl.1), 2000
Malaria es una patología reemergente en el mundo y en América en particular; se revisan aspectos epidemiológicos de la enfermedad en Perú. Las nuevas medidas de control propuestas por la OMS para reducir la mortalidad por malaria y su impacto socio-económico son: diagnóstico y tratamiento precoz de...

Monitorizaçäo das concentraçöes plasmáticas de quinina em pacientes com malária por P. Falciparum

A quinina é o quimioterápico de escolha no tratamento da malária falciparum resistente à cloroquina, importante patologia cuja incidência aumenta anualmente. Considerando-se o conjunto dos efeitos tóxicos da quinina (cinchonismo), as variaçöes na sua cinética durante episódios de malária näo ...