Abstract EphrinB2 plays a critical role in tumor growth. In this study, we studied the antitumor activity of imperatorin derivative IMP-1 in renal cell carcinoma (RCC) by regulating EphrinB2 pathway.. Results showed that IMP-1 inhibited the proliferation of 786-O cells in a dose- and time-dependent manne...
O crescimento desordenado de células no organismo, que pode invadir tecidos adjacentes ou órgãos em outras regiões do corpo, é denominado câncer (WHO, 2022a). A nomenclatura da doença corresponde ao local de foco inicial, e assim, os cânceres de mama, próstata, pulmão, colorretal, colo uterino ...
Estenosis de la Válvula Pulmonar/diagnóstico por imagen,
Estenosis de la Válvula Pulmonar/etiología,
Linfoma no Hodgkin/diagnóstico,
Linfoma no Hodgkin/complicaciones,
Estenosis de la Válvula Pulmonar/congénito,
Dolor en el Pecho/complicaciones,
Disnea/complicaciones,
Radiografía Torácica/métodos,
Toracoscopía/métodos,
Ecocardiografía/métodos,
Quimioterapia/métodos,
Combinación Trimetoprim y Sulfametoxazol/administración & dosificación,
Neoplasias/clasificación
Objetivo: descrever e reclassificar os diagnósticos de outras neoplasias de exames histopatológicos do colo do útero registrados no Sistema de Informação do Câncer (Siscan), Brasil, 2013-2020. Métodos: estudo descritivo dos diagnósticos compilados no campo "outras neoplasias malignas" do Siscan...
Previously, we evaluated the effect of trichostatin A (TSA) on the expression of DNA methyltransferase 1 (DNMT1) in Hepatocellular Carcinoma (HCC). Fragile histidine triad (FHIT) and WW domain-containing oxidoreductase (WWOX) are two of the most common down-regulated genes in many cancers located on chro...
A sanguinarina é um alcaloide capaz de inibir Bcl-xL, uma proteína antiapoptótica que se encontra superexpressa em linhagens tumorais e que está frequentemente relacionada à resistência destas frente a quimioterápicos antineoplásicos. No intuito de identificar potenciais agentes antitumorais, o o...
ABSTRACT Objectives : to investigate the impact of oncological surgical procedures on the muscle function of patients with and without nutritional risk. Methods: cross-sectional study conducted with cancer patients undergoing major operations between July 2018 to March 2019 in Cuiabá, Mato Grosso, Br...
Ethylenediamine tetraacetic acid (EDTA) is used in various medical applications. The aim of this study is to investigate the antitumor efficacy of EDTA alone or with cisplatin (Cis). Fifty male albino mice were used to assess the median lethal dose (LD50) of EDTA via intraperitoneal (i.p) injection. To d...
La calidad de vida en pacientes oncológicos es un constructo multidimensional que debe ser analizado con un enfoque integral.
Objetivo: determinar la calidad de vida percibida por pacientes oncológicos en estadio III y IV del Hospital José Carrasco Arteaga. Cuenca 2018. Metodología: estudio cuantita...
SUMMARY The increasing prevalence of neoplasias is associated with new clinical challenges, one of which is acute kidney injury (AKI). In addition to possibly constituting a clinical emergency, kidney failure significantly interferes with the choice and continuation of antineoplastic therapy, with progno...
