Results: 10

In vitro antiviral, antioxidant and in vivo antipyretic activity of three South Africa medicinal plants crude extracts

This study investigated anti-viral, antioxidant activity and anti-pyretic of crude extract from Artemisia afra, Artemisia absinthium and Pittiosporum viridflorum leaves. The crude extracts were prepared by maceration using aqueous, methanol and dichloromethane respectively. Ant...

Efficacy of oseltamivir compared with zanamivir in COPD patients with seasonal influenza virus infection: a randomized controlled trial

Braz. j. med. biol. res; 54 (2), 2021
Influenza viruses exacerbate chronic obstructive pulmonary disease (COPD) with considerable morbidity and mortality. Zanamivir and oseltamivir are effective in treating influenza. However, their efficacy in relieving influenza symptoms in COPD patients remains unknown, with the lack of controlled trials ...

A Therapeutic Oral Vaccine Candidate against Propionibacterium acnes: Preparation and Immunological Evaluation of Nanoparticles Encapsulated Sialidase-CAMP Fusion Protein

Abstract Acne Vulgaris is a common skin disease caused by Propionibacterium acnes, an anaerobic microbiota of human skin that plays a vital role in the pathology of acne. The aim of this study was to prepare nanoparticles containing an acne recombinant protein and determine its ability as an oral acne va...

El escándalo de la cloroquina
The chloroquine scandal

El autor aborda el caso de la cloroquina y la hidroxicloroquina en el contexto de la actual pandemia de COVID-19, a través de dos ejes centrales. Por un lado, el escándalo a nivel editorial y de comunicación de la evidencia, y por otro, el de la toma de decisiones en salud pública. Describe flagrante...

Evolution of equine influenza viruses (H3N8) during a Brazilian outbreak, 2015

Braz. j. microbiol; 49 (2), 2018
Abstract Equine influenza is one of the major respiratory infectious diseases in horses. An equine influenza virus outbreak was identified in vaccinated and unvaccinated horses in a veterinary school hospital in São Paulo, SP, Brazil, in September 2015. The twelve equine influenza viruses isolated belon...

Isolamento e caracterizaçäo de genes II da superfamília gp85/sialidases expressos nas formas amastigotas de Trypanosoma cruzi

O Trypanosoma cruzi é o protozoário flagelado causador da Doença de Chagas ou tripanosomíase americana, que atinge milhoes de pessoas na América Latina. Esse microorganismo apresenta um ciclo de vida complexo e o estágio evolutivo amastigota é a forma de replicaçao do parasita encontrada no hospe...

Bases fisiopatológicas para la prevención de las infecciones por Streptococcus pneumoniae
Physiopathological bases for preventing streptococcus pneumoniae infections

Streptococcus pneumoniae es un patógeno que coloniza la mucosa respiratoria superior y al mismo tiempo, puede ser la causa de enfermedades sumamente graves como neumonía, bacteriemia, meningitis y septicemia. Es necesario tener conocimiento sobre los factores de virulencia que determinan la dinámica d...

Influenza: una revisión de su quimioprofilaxis y terapéutica anti viral
Influenza: chemoprophylaxis and antiviral treatment

Rev. chil. infectol; 18 (2), 2001
Diferentes agentes antivirales están disponibles para ser utilizados de manera profiláctica o terapéutica en las infecciones por el virus influenza. Los inhibidores de la neuraminidasa viral tienen la ventaja de actuar eficazmente sobre el virus A y B de la influenza, logrando un mejor espectro antivi...