Results: 84

Investigating Morphological Changes of the Hippocampus After Prolonged Aerobic Exercise in Mice: Neural Function and Learning Capabilities

Int. j. morphol; 42 (3), 2024
SUMMARY: Both the academic and popular worlds have paid close attention to the link between exercise and cognitive performance. It is increasingly important to understand the numerous mechanisms by which exercise might influence cognitive abilities in view of the continuous societal issues caused by agin...

Acteoside Attenuates Recognition Memory Impairment in CUMS Rats via Regulating Synaptic Plasticity and mTOR Signaling Pathway

Int. j. morphol; 42 (2), 2024
SUMMARY: We evaluated the role and mechanism of acteoside in the regulation of memory impairment induced by chronic unpredictable mild stress (CUMS). CUMS was used to induce depression in rats and the successful establishment of CUMS model were verified by forced swimming test and sucrose preference test...

Oxytocin neuron activation by acute infusion of Montanoa genus plants in the Wistar rats

In tradition al Mexican medicine, plants from the Montanoa genus, family Asteraceae ( Montanoa tomentosa , Montanoa grandiflora , and Montanoa frutescens ) have been used to induce labor owing to their uterotonic properties like those produced by oxytocin (OXT). However, w hether infusions ...

El secuestro de la voluntad: bases moleculares de los cambios plásticos en la adicción
The hijacking of the will: molecular bases of plastic changes in addiction

Rev. psiquiatr. Urug; 88 (1), 2024
Todas las drogas de abuso tienen en común la activación del sistema cerebral del placer. Los análisis imagenológicos han arrojado resultados de cambios estructurales en el cerebro de adictos a la cocaína e imágenes cerebrales en sujetos adictos muestran una disminución de la producción de dopamin...

A neural cell automated analysis system based on pathological specimens in a gerbil brain ischemia model

Acta cir. bras; 39 (), 2024
Purpose: Amid rising health awareness, natural products which has milder effects than medical drugs are becoming popular. However, only few systems can quantitatively assess their impact on living organisms. Therefore, we developed a deep-learning system to automate the counting of cells in a gerbil mode...

Adult human neural cells in culture following traumatic brain injury

Rev. Ciênc. Saúde; 13 (3), 2023
Objective: The present study aims to evaluate the viability of adult human neural cells in culture obtained from traumatized brain tissues collected in emergency surgery procedures. Methods: Exploratory, descriptive, quantitative and cross-sectional study evaluating samples obtained from patients who und...

Investigating the role of Prefrontal Neurons in cognitive tasks through Fiber Photometry and Adapted Barnes Maze Protocols

The medial prefrontal cortex (mPFC) is essential in the execution of cognitive tasks, however very little is known on how these neurons are modulated during specific tasks and which subtype of neurons are responsible for so. Therego, with the intention of addressing this issue, we recorded mPFC gabaergic...

Study of the potential toxicity of adrenaline to neurons, using the SH-SY5Y human cellular model

Abstract Prolonged overexposure to catecholamines causes toxicity, usually credited to continuous adrenoceptor stimulation, autoxidation, and the formation of reactive pro-oxidant species. Non-differentiated SH-SY5Y cells were used to study the possible contribution of oxidative stress in adrenaline (ADR...

Rede neural artificial aplicada na análise da qualidade de vida de adolescentes

Objetivo: construir um modelo que explique a qualidade de vida relacionada à saúde entre adolescentes escolares a partir do instrumento KIDSCREEN-27 por meio da criação de uma rede neural artificial. Método: estudo transversal e analítico com 635 adolescentes utilizando-se o KIDSCREEN-27. Foi desen...