Introduction: Previous retrospective studies have demonstrated that the concentration of chemokine ligand CXCL13 in cerebrospinal fluid (CSF-CXCL13) is a promising biomarker in the diagnosis of neurosyphilis and, additionally, in the monitoring of therapeutic efficacy. Objective: To describe three cases ...
ABSTRACT Syphilis is a re-emerging sexually-transmitted infection, caused by the spirochete Treponema pallidum, that may penetrate early into the central nervous system. The venereal disease research laboratory test (VDRL) on the cerebrospinal fluid (CSF) is the most widely used for neurosyphilis diagnos...
Análisis de Varianza,
Anticuerpos Antibacterianos/líquido cefalorraquídeo,
Estudios de Casos y Controles,
Neurosífilis/sangre,
Neurosífilis/líquido cefalorraquídeo,
Neurosífilis/diagnóstico,
Neurosífilis/inmunología,
Valores de Referencia,
Reproducibilidad de los Resultados,
Sensibilidad y Especificidad,
Estadísticas no Paramétricas,
Serodiagnóstico de la Sífilis/métodos
Medical literature shows that the co-infection of syphilis and human immunodeficiency virus
(HIV) is increasing dramatically worldwide. HIV infection and syphilis have a synergistic
relationship. Syphilis increases the risk of HIV transmission and acquisition, while HIV affects
the presentation, diagnosi...
ABSTRACT Background During the first decade of this century, a significant increase in the incidence of syphilis was documented. Objective To study clinical and laboratory characteristics of central nervous system and ocular syphilis. Methods A retrospective case series of 13 patients with a clinic...
Resumo Aos 44 anos, após sofrer um colapso em Turim, o filósofo Friedrich Nietzsche recebeu o diagnóstico médico de neurossífilis. Devido à ausência de autópsia em seu corpo, tal diagnóstico médico vem sendo questionado historicamente. Realizou-se a revisão da literatura disponível sobre o di...
ABSTRACT Lumbar puncture in neurologically asymptomatic HIV+ patients is still under debate. There are different criteria for detecting neurosyphilis through cerebrospinal fluid (CSF), especially in cases that are negative through the Venereal Disease Research Laboratory (VDRL), regarding cellularity and...
A sífilis é um agravo infectocontagioso causado pelo Treponema pallidum, de transmissão predominantemente sexual, que afeta 12 milhões de pessoas por ano no mundo. Se não curada em suas fases iniciais, predispõe a complicações potencialmente graves. Uma dessas complicações é a neurossífilis, ...
The aim of this paper is to report two cases of neurosyphilis and uveitis diagnosed by an ophthalmologist in an immunocompetent couple. In addition to
reporting cases the authors discuss ethical issues of communication of diagnosis to partners of patients (AU)...
