Abstract The assessment of the comparative effect of biosal (phytopesticide), deltamethrin, and lambda-cyhalothrin (pyrethroids) were made against two fodder pests, Hermolaus modestus and Hermolaus ocimumi by filter paper impregnation method. The activity of total protein contents, GPT (glutamic-pyruvic ...
Abstract: Objective: The feasibility of the use of WHO impregnated paper and biochemical assays to determine lethal concentrations (LC50 and LC99) and insecticide metabolic enzyme levels of Triatoma dimidiata. Materials and methods: LC50 and LC99 were calculated with WHO papers impregnated at different...
Resistencia a los Insecticidas,
Insecticidas/toxicidad,
Malatión/toxicidad,
Nitrilos/toxicidad,
Propoxur/toxicidad,
Piretrinas/toxicidad,
Triatoma/efectos de los fármacos,
Acetilcolinesterasa/análisis,
Sistema Enzimático del Citocromo P-450/análisis,
Esterasas/análisis,
Estudios de Factibilidad,
Glutatión Transferasa/análisis,
Dosificación Letal Mediana,
Oxigenasas de Función Mixta/análisis,
Ninfa/efectos de los fármacos,
Ninfa/enzimología,
Triatoma/enzimología,
Organización Mundial de la Salud
Abstract INTRODUCTION: The use of insecticide-impregnated dog collars is a potentially useful tool for the control of visceral leishmaniasis. The objective of the present study was to perform a cost-effectiveness analysis of a program based on insecticide-impregnated collars compared to traditional vis...
SUMMARY: An alternative superovulator to replace clomiphene citrate is needed as clomiphene citrate is associated with low pregnancy rates. Anastrozole is an effective superovulator, but it has not been well researched. In order to determine the effectiveness of anastrozole as a superovulator and to comp...
Nitrilos/farmacología,
Triazoles/farmacología,
Vinculina/efectos de los fármacos,
Integrinas/efectos de los fármacos,
Adhesiones Focales/efectos de los fármacos,
Microscopía Confocal,
Microscopía Fluorescente,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Útero/efectos de los fármacos,
Células Epiteliales/efectos de los fármacos,
Vinculina/fisiología,
Vinculina/genética,
Integrinas/fisiología,
Integrinas/genética,
Ratas Wistar
BACKGROUND There is little information on the effect of using deltamethrin-impregnated dog collars for the control of canine visceral leishmaniasis. OBJECTIVES The objective of this study was to evaluate the effectiveness of the use of 4% deltamethrin-impregnated collars (Scalibor®) in controlling vi...
ABSTRACT Aromatase is a cytochrome P450 enzyme (CYP19A1 isoform) able to catalyze the conversion of androgens to estrogens. The aromatase gene mutations highlighted the action of estrogen as one of the main regulators of bone maturation and closure of bone plate. The use of aromatase inhibitors (AI) in b...
Summary Aromatase inhibitors have emerged as an alternative endocrine therapy for the treatment of hormone sensitive breast cancer in postmenopausal women. The use of third-generation inhibitors represented by exemestane, letrozol and anastrozole is currently indicated. Anastrozole is a nonsteroidal comp...
Anastrozol,
Antineoplásicos Hormonales/farmacocinética,
Antineoplásicos Hormonales/uso terapéutico,
Inhibidores de la Aromatasa/farmacocinética,
Inhibidores de la Aromatasa/uso terapéutico,
Neoplasias de la Mama/tratamiento farmacológico,
Neoplasias de la Mama/prevención & control,
Quimioprevención/métodos,
Quimioterapia Adyuvante,
Nitrilos/farmacocinética,
Nitrilos/uso terapéutico,
Posmenopausia,
Reproducibilidad de los Resultados,
Tamoxifeno/farmacocinética,
Tamoxifeno/uso terapéutico,
Resultado del Tratamiento,
Triazoles/farmacocinética,
Triazoles/uso terapéutico
Maximum androgen blockade is the standard endocrine treatment for advanced prostate cancer. Interstitial lung disease in different degrees of severity, with low mortality and excellent response to treatment may appear with its use. We report a 77 years old patient with advanced prostate cancer who develo...
Antagonistas de Andrógenos/efectos adversos,
Antinematodos/efectos adversos,
Enfermedades Pulmonares Intersticiales/inducido químicamente,
Adenocarcinoma/tratamiento farmacológico,
Anilidas/efectos adversos,
Biopsia,
Progresión de la Enfermedad,
Resultado Fatal,
Enfermedades Pulmonares Intersticiales/patología,
Nitrilos/efectos adversos,
Neoplasias de la Próstata/tratamiento farmacológico,
Tomografía Computarizada por Rayos X,
Compuestos de Tosilo/efectos adversos
PURPOSE: To evaluate the effects of letrozole (Ltz) in carcinogen+estrogen-induced endometrial hyperplasia. METHODS: BALB/c female mice were divided into four groups of 12 animals each receiving an intrauterine dose of N-ethyl-N-nitrosourea (ENU) and weekly subcutaneous injections of estradiol hexaid...
Inhibidores de la Aromatasa/farmacología,
Carcinogénesis/efectos de los fármacos,
Hiperplasia Endometrial/tratamiento farmacológico,
Nitrilos/farmacología,
Triazoles/farmacología,
Adenocarcinoma/tratamiento farmacológico,
Adenocarcinoma/etiología,
Antineoplásicos Hormonales/farmacología,
Inhibidores de la Aromatasa/uso terapéutico,
Carcinogénesis/patología,
Hiperplasia Endometrial/inducido químicamente,
Hiperplasia Endometrial/patología,
Neoplasias Endometriales/tratamiento farmacológico,
Neoplasias Endometriales/etiología,
Endometrio/efectos de los fármacos,
Endometrio/patología,
Estradiol/sangre,
Etilnitrosourea,
Acetato de Medroxiprogesterona/farmacología,
Ratones Endogámicos BALB C,
Nitrilos/uso terapéutico,
Progesterona/sangre,
Reproducibilidad de los Resultados,
Factores de Tiempo,
Resultado del Tratamiento,
Triazoles/uso terapéutico
Se logró la síntesis de 4-amino-2-quinolomas a partir de N-fenilcianoacetamidas y de 4-aminoquinolinas a partir de 2-aminobenzonitrilo y compuestos Beta-dicarbonílicos. En ambos casos se utilizaron ácidos Lewis como catalizadores....
