Dynamic S-palmitoylation of proteins is the addition of palmitic acid by zDHHC palmitoyl transferases (PATs) and depalmitoylation by palmitoyl protein thioesterases (PPTs). A putative PAT (TcPAT1) has been previously identified in Trypanosoma cruzi, the etiological agent of Chagas disease. Here we analys...
Background: Several investigations report to rosemary as a plant rich in bioactive components with antioxidant potential, in this work, a rosemary extract was obtained that combined with ascorbyl palmitate provides a synergistic protection to a high fat diet (palm olein). Objectives: The objective of thi...
Solid lipid nanoparticles (SLN) were recently proposed as carriers for various pharmaceutical and cosmetic actives. These lipid nanoparticles can act as moisturizers and physical sunscreens on their own. Therefore, the full potential of these carriers has yet to be determined. The present study was aimed...
A atmosfera modificada é amplamente utilizada para aumentar a vida de prateleira e a qualidade de carnes refrigeradas. Entretanto, o uso de elevadas concentrações de oxigênio pode promover a oxidaço lipídica. O emprego de antioxidantes naturais, utilizados de forma endógena ou exógena, atua na pr...
El presente trabajo permite la estandarización y control de calidad de los métodos utilizados en los laboratorios regionales del país. Las deficiencias por micronutientes plantean graves daños a la salud y a la economía de los pueblos, sus consecuencias van desde el incremento de la mortalidad, alte...
A homogeneidade das suspensoes farmaceuticas e de importancia fundamental na terapeutica, no aspecto da correta e constante dosagem a cada administracao. A influencia dos tensoativos nao ionicos foi estudada na estabilidade das suspensoes de estearato e palmitato de cloranfenicol e estearato e estolato d...
