Plesiomonas shigelloides exports a lethal cytotoxic-enterotoxin (LCE) by membrane vesicles
Braz. j. infect. dis; 20 (6), 2016
ABSTRACT Plesiomonas shigelloides isolated from water in Brazil was previously described as a hemorrhagic heat-labile cytotoxic-enterotoxin producer. We purified this toxin from culture supernatants using ion metallic affinity chromatography (IMAC) followed by molecular exclusion chromatography. The pure...
Supervivencia Celular/efectos de los fármacos, Chlorocebus aethiops, Vesículas Citoplasmáticas, Enterotoxinas/farmacología, Dosificación Letal Mediana, Microscopía Electrónica de Rastreo, Pruebas de Neutralización, Plesiomonas/metabolismo, Plesiomonas/patogenicidad, Plesiomonas/ultraestructura, Ríos/microbiología, Células Vero, Factores de Virulencia