Single nucleotide polymorphisms (SNPs, rs12979860 e rs8099917) in the Interferon Lambda 4 gene (IFNL4, formerly IFNL3and/or IL28B) has been associated with failure in the innate immune response, sustained virological response in hepatitis C, and HTLV-1-associated myelopathy (HAM) development. To search...
Ullah, I;
Afridi, S G;
Khan, A U;
Israr, M;
Ali, A;
Shams, S;
Jabeen, H;
Rasool, A;
Akbar, F;
Rahat, M A;
Haris, M;
Khan, A;
Siraj, M;
Shah, M.
Plasmodium vivax is the most common human malaria parasite in Asian countries including Pakistan. Present study was designed to explore the genetic diversity of plasmodium vivax genotypes based on Pvmsp-3α and Pvmsp-3βgenes using allelic specific nested PCR and RFLP assays markers from field isolates i...
Background: The intrinsic sensitivity limitations of basic parasitological methods, along with the particular biological characteristics of parasites, make these methods ineffective to differentiate morphologically indistinguishable species. Molecular detection and characterization techniques could be u...
Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic disease in cats. However, scarce data on its prevalence are available in Brazil. Persian cats and Persian-related breeds were assessed by molecular genotyping for a C to A transversion in exon 29 of PKD1 gene to determine ADP...
Conceição, Emilyn Costa;
Salvato, Richard Steiner;
Gomes, Karen Machado;
Guimarães, Arthur Emil dos Santos;
da Conceição, Marília Lima;
Souza e Guimarães, Ricardo José de Paula;
Sharma, Abhinav;
Furlaneto, Ismari Perini;
Barcellos, Regina Bones;
Bollela, Valdes Roberto;
Anselmo, Lívia Maria Pala;
Sisco, Maria Carolina;
Niero, Cristina Viana;
Ferrazoli, Lucilaine;
Refrégier, Guislaine;
Lourenço, Maria Cristina da Silva;
Gomes, Harrison Magdinier;
de Brito, Artemir Coelho;
Catanho, Marcos;
Duarte, Rafael Silva;
Suffys, Philip Noel;
Lima, Karla Valéria Batista.
Molecular-typing can help in unraveling epidemiological scenarios and improvement for disease control strategies. A literature review of Mycobacterium tuberculosis transmission in Brazil through genotyping on 56 studies published from 1996-2019 was performed. The clustering rate for mycobacterial intersp...
ABSTRACT Objective: To evaluate the possible association of a polymorphism in the gene encoding methylenetetrahydrofolate dehydrogenase 1 (MTHFD1), 1958G>A, with the susceptibility to orofacial cleft in an Indonesian population. Material and Methods: A total of 200 stored secondary biological sample...
BACKGROUND The genetic heterogeneity of Leishmania parasites is a major factor responsible for the wide variety of Leishmania-associated manifestations. Consequently, understanding the genetic make-up of Leishmania species using suitable molecular markers is an important component of realising local and...
Abstract INTRODUCTION: The clinical manifestations of cryptococcosis are usually associated with the infecting agents Cryptococcus neoformans (CN) and C. gattii (CG) species complexes and the host. In this study, non-HIV-infected patients, at a university hospital in southeastern Brazil, had epidemiolo...
BACKGROUND: BMPR-1B is part of the transforming growth factor β super family and plays a pivotal role in ewe litter size. Functional loss of exon-8 mutations in the BMPR-1B gene (namely the FecB gene) can increase both the ewe ovulation rate and litter size. RESULTS: This study constructed a eukaryotic...
Receptores de Proteínas Morfogenéticas Óseas de Tipo 1/genética,
Eucariontes/genética,
Ovario/metabolismo,
Mapas de Interacción de Proteínas/genética,
Receptores de Proteínas Morfogenéticas Óseas de Tipo 1/metabolismo,
Eucariontes/metabolismo,
Biología Computacional,
Genotipo,
Espectrometría de Masas,
Mutación,
Reacción en Cadena de la Polimerasa,
Polimorfismo de Longitud del Fragmento de Restricción,
Ovinos,
Transducción de Señal
Abstract Genetic and epigenetic changes have been associated with periodontitis in various genes; however, little is known about genes involved in epigenetic mechanisms and in oxidative stress. Objective: This study aims to investigate the association of polymorphisms C677T in MTHFR (rs1801133) and W...
Estudios de Casos y Controles,
Catalasa/genética,
ADN (Citosina-5-)-Metiltransferasas/genética,
Metilación de ADN/genética,
Estudios de Asociación Genética,
Genotipo,
Metilenotetrahidrofolato Reductasa (NADPH2)/genética,
MicroARNs/genética,
Periodontitis/genética,
Reacción en Cadena de la Polimerasa,
Polimorfismo Genético,
Polimorfismo de Longitud del Fragmento de Restricción,
Superóxido Dismutasa-1/genética
