Results: 6

Estudo de alterações moleculares na neoplasia sólida pseudopapilar do pâncreas

Study of molecular alterations in solid pseudopapillary neoplasm of the pancreas

Ribeiro, Bruna dos Santos Paiva.

INTRODUÇÃO: A neoplasia sólida pseudopapilar do pâncreas (NSPP) é rara e de baixa malignidade. Constitui cerca de 1-2% de todas as neoplasias pancreáticas exócrinas e ocorre principalmente em mulheres jovens. A heterogeneidade intratumoral tem sido descrita em vários tipos de tumor, incluindo a N...

Neoplasias Pancreáticas/genética, Neoplasias Pancreáticas/tratamiento farmacológico, Metilación, Páncreas, Polimorfismo de Longitud del Fragmento de Restricción/genética, Polimorfismo Genético, Heterogeneidad Genética, Biología Molecular, Epigenómica

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Molecular epidemiology of Mycobacterium tuberculosis in Brazil before the whole genome sequencing era: a literature review

Conceição, Emilyn Costa; Salvato, Richard Steiner; Gomes, Karen Machado; Guimarães, Arthur Emil dos Santos; da Conceição, Marília Lima; Souza e Guimarães, Ricardo José de Paula; Sharma, Abhinav; Furlaneto, Ismari Perini; Barcellos, Regina Bones; Bollela, Valdes Roberto; Anselmo, Lívia Maria Pala; Sisco, Maria Carolina; Niero, Cristina Viana; Ferrazoli, Lucilaine; Refrégier, Guislaine; Lourenço, Maria Cristina da Silva; Gomes, Harrison Magdinier; de Brito, Artemir Coelho; Catanho, Marcos; Duarte, Rafael Silva; Suffys, Philip Noel; Lima, Karla Valéria Batista.

Mem. Inst. Oswaldo Cruz; 116 (), 2021

Molecular-typing can help in unraveling epidemiological scenarios and improvement for disease control strategies. A literature review of Mycobacterium tuberculosis transmission in Brazil through genotyping on 56 studies published from 1996-2019 was performed. The clustering rate for mycobacterial intersp...

Técnicas de Tipificación Bacteriana, Brasil/epidemiología, Genotipo, Repeticiones de Minisatélite/genética, Epidemiología Molecular, Mycobacterium tuberculosis/genética, Mycobacterium tuberculosis/aislamiento & purificación, Polimorfismo de Longitud del Fragmento de Restricción/genética, Secuenciación Completa del Genoma

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MTHFR gene polymorphisms in hypothyroidism and hyperthyroidism among Jordanian females

Abu-Hassan, Diala W; Alhouri, Abdullah N; Altork, Nadera A; Shkoukani, Zakaria W; Altamimi, Tamer Salhab; Alqaisi, Omar M; Mustafa, Baha.

Arch. endocrinol. metab. (Online); 63 (3), 2019

ABSTRACT Objective Methylenetetrahydrofolate reductase (MTHFR) is involved in DNA methylation that is associated with autoimmune pathology. We investigated the association between MTHFR genetic polymorphisms at g.677C>T and g.1298A>C and their haplotypes, and the risk of thyroid dysfunction among...

Alelos, Estudios de Casos y Controles, Metilación de ADN, Predisposición Genética a la Enfermedad, Genotipo, Haplotipos, Hipertiroidismo/genética, Hipotiroidismo/genética, Jordania, Metilenotetrahidrofolato Reductasa (NADPH2)/genética, Reacción en Cadena de la Polimerasa, Polimorfismo de Longitud del Fragmento de Restricción/genética, Polimorfismo de Nucleótido Simple/genética, Factores de Riesgo

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Polymorphisms in NAT2 (N-acetyltransferase 2) gene in patients with systemic lupus erythematosus

Santos, Elaine Cristina Lima dos; Pinto, Amanda Chaves; Klumb, Evandro Mendes; Macedo, Jacyara Maria Brito.

Rev. bras. reumatol; 56 (6), 2016

ABSTRACT Objective: To investigate potential associations of four substitutions in NAT2 gene and of acetylator phenotype of NAT2 with systemic lupus erythematosus (SLE) and clinical phenotypes. Methods: Molecular analysis of 481C>T, 590G>A, 857G>A, and 191G>A substitutions in the NAT2 gene ...

Arilamina N-Acetiltransferasa/genética, Predisposición Genética a la Enfermedad/genética, Genotipo, Lupus Eritematoso Sistémico/genética, Polimorfismo de Longitud del Fragmento de Restricción/genética

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Clinical characteristics and frequency of TLR4 polymorphisms in Brazilian patients with ankylosing spondylitis

Machado, Natalia Pereira; Nogueira, Eliana; Oseki, Karen; Ebbing, Pâmela Carolina Cruz; Origassa, Clarice Silvia Taemi; Mohovic, Tatiane; Câmara, Niels Olsen Saraiva; Pinheiro, Marcelo de Medeiros.

Rev. bras. reumatol; 56 (5), 2016

ABSTRACT Objectives: Innate immunity is involved in the physiopathology of ankylosing spondylitis (AS), with the participation of Gram-negative bacteria, modulation of human leukocyte antigen (HLA) B27 and the involvement of pattern recognition receptors, such as Toll-like receptors (TLRs). The aim of t...

Brasil, Estudios de Casos y Controles, Estudios Transversales, Predisposición Genética a la Enfermedad, Antígeno HLA-B27/genética, Polimorfismo de Longitud del Fragmento de Restricción/genética, Espondilitis Anquilosante/genética, Receptor Toll-Like 4/genética

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Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in psoriasis in southern Turkey

Izmirli, Muzeyyen; Sen, Bilge Bulbul; Rifaioglu, Eminenur; Gogebakan, Bulent; Aldemir, Ozgur; Sen, Tuba; Ekiz, Ozlem; Alptekin, Davut.

An. bras. dermatol; 91 (5), 2016

Abstract: Background: Psoriasis is a multigenic and multifactorial dermatological disease linked to cardiovascular diseases. Increased levels of homocysteine in patients with psoriasis have been demonstrated in many studies. The most frequently investigated genetic defect that plays a role in homocystei...

Metilenotetrahidrofolato Reductasa (NADPH2)/genética, Polimorfismo Genético/genética, Psoriasis/enzimología, Polimorfismo de Longitud del Fragmento de Restricción/genética, Psoriasis/genética, Factores de Riesgo, Turquía

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