Results: 15

Development, characterization and anti - Mycobacterium tuberculosis activity of solid lipid nanoparticles for oral Piper corcovadensis roots extract delivery

The present study thus aimed at the development and physicochemical characterization of solid lipid nanoparticles loaded with crude extract of Piper corcovadensis roots (SLN - CEPc) and chitosan - coated solid lipid nanoparticles loaded with crude extract of P. corcovadensis roots (...

Nanopartículas como transportadores de fármacos: una herramienta prometedora contra la tuberculosis

RESUMEN La Organización Mundial de la Salud (OMS) ubica a la tuberculosis (TB) como uno de los problemas de salud más preocupantes en la actualidad, y señala que se requieren de acciones novedosas para controlar su expansión y, de esta manera, alcanzar una de las metas establecidas en los Objetivos d...

Immune response and biochemistry of calves immunized with rMSP1a ( Anaplasma marginale) using carbon nanotubes as carrier molecules

Abstract Vaccination against Anaplasma marginale has been considered an important control strategy for bovine anaplasmosis. Recently, mice immunized with rMSP1 a linked to carbon nanotubes (MWNT) showed significant immune responses, generating a new possibility for use of an inactivated vaccine. The obj...

Calcium hydroxide associated with a new vehicle: Psidium cattleianum leaf extracts. Tissue response evaluation

Abstract The aim of this study was to evaluate edemogenic activity and subcutaneous inflammatory reaction induced by Psidium cattleianum leaf extracts associated with Ca(OH)2. Thirty male Wistar rats, split equally into three groups [aqueous extract + Ca(OH)2; ethanolic extract + Ca(OH)2; and propylene g...

Advances in the use of nanocarriers for cancer diagnosis and treatment

Einstein (Säo Paulo); 14 (1), 2016
ABSTRACT The use of nanocarriers as drug delivery systems for therapeutic or imaging agents can improve the pharmacological properties of commonly used compounds in cancer diagnosis and treatment. Advances in the surface engineering of nanoparticles to accommodate targeting ligands turned nanocarriers at...

Evaluation of antimicrobial activity and cell viability of Aloe vera sponges

Electron. j. biotechnol; 16 (1), 2013
Background: Aloe vera L., member of the Liliaceae family, has been shown to stimulate cell proliferation and contribute to healing and angiogenesis, has anti-bacterial, anti-fungal and anti-inflammatory activity. In addition, Aloe vera can be used as a support for drug transport. Our objective is to eval...

Histological Evaluation of the Bone Repair Using Mineral Trioxide Aggregate Combined to a Material Carrier

Int. j. morphol; 25 (4), 2007
The aim of this study was to present a possible carrier for MTA, monoolein gel, with the objective to maintain this material in the place that was inserted and verify if this procedure is able to optimize its action. The data were evaluated by histomorphometric method and submitted to statistical analysi...

Biochemical Analysis by Calcium Determination on the Newly Formed Bone in Critical Bone Defects Submitted to Different Treatments: A Pilot Study

Int. j. morphol; 25 (3), 2007
The aim of this study was to evaluate the calcium dosage of the newly formed bone, in critical bone defects created on the calvarial tissue and filled by different substances, in male Wistar rats. A cylindrical critical bone defect (6x2mm) was created in the posterior portion, left side, on the calvarial...

Associação de derivados do quimioterápico daunorrubicina à nanoemulsão lipídica que se liga aos receptores da LDL: estudos pré-clínicos

A daunorrubicina é utilizada no tratamento da leucemia mielóide aguda cujo uso é muito limitado devido à alta cardiotoxicidade. Neste trabalho foi feita a sua modificação química e associação à uma nanoemulsão lipídica que se liga aos receptores da LDL, a LDE, como um meio de reduzir a toxici...

Perú: estadísticas de producción, tráfico y consumo de drogas, 1996-97

Presenta información estadística: de la superficie dedicada al cultivo tanto tradicional como ilícito de la hoja de coca, muestra su comercialización y los aspectos inherentes al desarrollo alternativo a través del cultivo de productos agrícolas diversos; tráfico ilícito de drogas e incineracione...