Background: The bioactive peptides derived from snake venoms of the Viperidae family species have been promising as therapeutic candidates for neuroprotection due to their ability to prevent neuronal cell loss, injury, and death. Therefore, this study aimed to evaluate the cytoprotective effects of a sy...
Castoldi, Robson Chacon;
Marcelo, Henrique Izaias;
Félix, Andressa Eulina da Cruz;
Silva, Jonathan Borges Peixoto;
Caetano, Heliard Rodrigues dos Santos;
Garcia, Thiago Alves;
Ozaki, Guilherme Akio Tamura;
Giometti, Inês Cristina;
Camargo Filho, José Carlos Silva;
Belangero, William Dias.
O objetivo deste estudo foi avaliar o efeito da aplicação de hormônio do crescimento (Growth Hormone - GH) e treinamento de força (TF) na composição do
tecido ósseo de ratos Wistar a partir da Espectroscopia Raman. 40 ratos machos foram distribuídos de forma aleatória em quatro grupos: controle ...
Ejercicio Físico,
Espectrometría Raman,
Carbohidratos,
Colesterol,
Colágeno,
51607,
Fosfolípidos,
Hormona del Crecimiento,
Lípidos,
Peso Corporal,
Ratas Wistar,
Entrenamiento de Fuerza,
Glicerol,
Prolina,
Análisis de Varianza,
Análisis Espectral,
Fémur,
Metabolismo,
Huesos
In this study, we investigated the proline and protease production of different bacteria in several organic waste materials. Our aim was to produce proline and protease economically in waste that is abundantly available while reducing its environmental impact. 5 ml of different organic waste materials (O...
BACKGROUND: Apple is one of the oldest and most valuable fruits. Water restriction is one of the major problems in the production of this fruit in some planting areas. METHODS: Effects of kaolin spray treatments were studied on two early apple cultivars of Golab and Shafi-Abadi under sustained deficit ir...
Background Conotoxins have become a research hotspot in the neuropharmacology field for their high activity and specificity in targeting ion channels and neurotransmitter receptors. There have been reports of a conotoxin acting on two ion channels, but rare reports of a conotoxin acting on three ion chan...
Souza, T F G;
Pierdoná, T M;
Macedo, F S;
Aquino, P E A;
Rangel, G F P;
Duarte, R S;
Silva, L M A;
Viana, G S B;
Alves, A P N N;
Montenegro, R C;
Wilke, D V;
Silveira, E R;
Alencar, N M N.
It was previously demonstrated that the methanol fraction of Sideroxylon obtusifolium (MFSOL) promoted anti-inflammatory and healing activity in excisional wounds. Thus, the present work investigated the healing effects of MFSOL on human keratinocyte cells (HaCaT) and experimental burn model injuries. Ha...
Some amino acids can protect mammalian sperm cells against oxidation during thermal stress caused by freezing/thawing. Thus, the objective was to evaluate the protective action of the association of the amino acids L-proline (Pro) and L-glutamine (Glu) against the cryoinjury caused to sheep sperm after c...
Abstract: Cost-effectiveness analysis is essential in health decision making. Several countries use it as synthesis of evidence to incorporate health technologies. The protease inhibitors (PI) boceprevir (BOC) and telaprevir (TVR) are indicated for chronic hepatitis C treatment and were incorporated in g...
Antivirales/economía,
Antivirales/uso terapéutico,
Brasil,
Análisis Costo-Beneficio,
Quimioterapia Combinada,
Genotipo,
Hepacivirus,
Hepatitis C Crónica/tratamiento farmacológico,
Hepatitis C Crónica/economía,
Interferón alfa-2,
Interferón-alfa,
Oligopéptidos,
Polietilenglicoles,
Prolina/análogos & derivados,
Años de Vida Ajustados por Calidad de Vida,
Proteínas Recombinantes,
Ribavirina
Abstract In this study, the activities of antioxidant enzymes, photosynthetic pigments, proline and carbohydrate contents in Pitcairnia encholirioides under ex vitro conditions of water deficit were evaluated. Results show that plants under progressive water stress, previously in vitro cultured in media ...
Antioxidantes/metabolismo,
Bromeliaceae/enzimología,
Bromeliaceae/fisiología,
Metabolismo de los Hidratos de Carbono,
Sequías,
Longevidad,
Fotosíntesis/fisiología,
Pigmentos Biológicos,
Proteínas de Plantas/metabolismo,
Prolina/metabolismo,
Agua/metabolismo
Turones, L C;
Cruz, K R da;
Camargo-Silva, G;
Reis-Silva, L L;
Graziani, D;
Ferreira, P M;
Galdino, P M;
Pedrino, G R;
Santos, R;
Costa, E A;
Ianzer, D;
Xavier, C H.
The heptapeptide Bj-PRO-7a, isolated and identified from Bothrops jararaca (Bj) venom, produces antihypertensive and other cardiovascular effects that are independent on angiotensin converting enzyme inhibition, possibly relying on cholinergic muscarinic receptors subtype 1 (M1R). However, whether Bj-PRO...
Ansiedad,
Conducta Animal/efectos de los fármacos,
Conducta Animal/fisiología,
Venenos de Crotálidos/química,
Depresión,
Conducta Exploratoria/efectos de los fármacos,
Oligopéptidos/aislamiento & purificación,
Oligopéptidos/farmacología,
Prolina/aislamiento & purificación,
Prolina/farmacología,
Ratas Wistar
