Results: 16

Development of the Goose Tongue Filiform Papillae: Could it be Tooth-Like Sense Organs?

Int. j. morphol; 41 (6), 2023
SUMMARY: The geese's tongue filiform papillae are particularly long, and exhibit the same morphology of a tooth, evoking the lingual teeth of several fishes. In adult animals, they contain numerous mechanical Herbst's corpuscles but no taste buds. In the embryo, they appear since stage 38 and acquire the...

O papel de proteínas das vias WNT/ß-Catenina, TGF-ß/BMP4 e SHH na odontogênese e odontomas
The role of proteins from the WNT/ß-Catenin, TGF-ß/BMP4 and SHH pathways in odontogenesis and odontomas

O desenvolvimento do dente depende de uma série de interações sinalizadoras recíprocas entre o epitélio oral (EO) e o ectomesênquima derivado da crista neural, a via WNT com o TGF-β e BMP4 tem sido implicada na tumorigênese. A via de sinalização tipo Wingless (Wnt) / β-catenina é essencial pa...

Vismodegib for treatment of periocular basal cell carcinoma - 6-year experience from a tertiary cancer center

An. bras. dermatol; 96 (6), 2021
Abstract Background: The treatment of advanced periocular basal cell carcinomas becomes a challenge as surgery may involve highly mutilating procedures. Vismodegib is the first selective hedgehog inhibitor approved for the treatment of locally advanced tumors or metastatic disease. Objective: Analyze t...

Effects of vitamin e on the epithelial-mesenchymal transition in testicular development exposed to valproic acid

Int. j. morphol; 39 (4), 2021
SUMMARY: In testicular differentiation, somatic cells must adopt a specific destiny towards sustentacular, peritubular and interstitial cells, being fundamental for the morphogenesis of seminiferous tubules, mediated by morphogens such as Desert Hedgehog (DHH), insulin-like growth factor-1 (IGF-1) and fi...

Effect of dietary nutrition on tail fat deposition and evaluation of tail-related genes in fat-tailed sheep

BACKGROUND: The effects of dietary nutrition on tail fat deposition and the correlation between production performance and the Hh signaling pathway and OXCT1 were investigated in fat-tailed sheep. Tan sheep were fed different nutritional diets and the variances in tail length, width, thickness and tail w...

Desarrollo embriofetal del iris: inmunotinción del morfógeno Shh

Int. j. morphol; 37 (1), 2019
RESUMEN: Para que se desarrolle el iris, se requiere una especificación de la capa periférica de la copa óptica a un destino no neuronal y además la migración de células mesenquimales perioculares. Nuestro objetivo fue reconocer los cambios histológicos de los derivados periféricos de la copa óp...

Avaliação genética nos diferentes fenótipos da Doença Pulmonar Obstrutiva Crônica
Genetic evaluation of the different phenotypes of Chronic Obstructive Pulmonary Disease

A doença pulmonar obstrutiva crônica (DPOC) caracteriza-se por apresentação heterogênea e, recentemente, tem-se tentado subdividir os pacientes em diferentes fenótipos, sendo os principais: Exacerbador, Misto DPOC-asma e Enfisema hiperinsuflador. Diversos genes têm sido avaliados quanto à possív...

Factores de crecimiento incluidos en terminologia embryologica: análisis crítico

Int. j. morphol; 36 (2), 2018
Cada término incluido en Terminologia Embryologica (TE), publicada en 2013 y con una segunda edicición en 2017 sujeta a aprobación por la Federación Internacional de Programas de Terminología Anatómica (FIPAT), se debe estructurar en base a sus principios: los nombres deben tener un valor informati...

Inmunolocalización de Sonic hedgehog en el desarrollo embrio-fetal de ratones ( Mus musculus )

Int. j. morphol; 36 (2), 2018
Sonic hedgehog (Shh) es un morfógeno esencial para el desarrollo de diversas estructuras, tales como notocorda, placa del piso del tubo neural, miembros, entre otros. Se buscó determinar la inmunolocalización de Shh en embriones y fetos de ratón. Para ello, se eutanasiaron 10 ratones gestantes (Mus m...