Design and optimization of novel in situ gel of mercaptopurine for sustained drug delivery
Braz. j. pharm. sci; 50 (1), 2014
Mercaptopurine is a purine antagonist, belonging to the class of antimetabolites. Its oral absorption is erratic and variable throughout GIT, with bioavailability of 5-37% and belongs to Biopharmaceutical Classification System (BCS) class IV. The focus of the present study was to improve solubility of me...