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Anticancer, anti-inflammatory and analgesic activities of aminoalcohol-based quinoxaline small molecules

Neri, Jannyely Moreira; Siqueira, Paula Emília Apolônio; Oliveira, Ana Luiza Cabral de Sá Leitão; Araújo, Renata Mendonça; Araújo Júnior, Raimundo Fernandes de; Martins, Agnes Andrade; Marques, Isabelle de Lima; Silva, Rafaela Alcindo; Araújo, Aurigena Antunes de; Menezes, Fabrício Gava.
Acta cir. bras; 39 (), 2024
Purpose: Bioactive molecules are relevant to fight cancer and associated conditions. Quinoxaline is a privileged N-heterocycle, notably as anticancer agents. Herein, we report the evaluation of the quinoxaline derivatives DEQX and OAQX as anticancer agents, as well as in function of their anti-inflammato...
Anticarcinógenos, Antiinflamatorios, Analgésicos, Quinoxalinas, Apoptosis
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Cometabolic biodegradation of quizalofop-p-ethyl by Methylobacterium populi YC-XJ1 and identification of QPEH1 esterase

Li, Xianjun; Wang, Junhuan; Wu, Wei; Jia, Yang; Fan, Shuanghu; Su Hlaing, Thet; Khokhar, Ibatsam; Yan, Yanchun.
Electron. j. biotechnol; 46 (), 2020
BACKGROUND: Quizalofop-p-ethyl (QPE), a unitary R configuration aromatic oxyphenoxypropionic acid ester (AOPP) herbicide, was widely used and had led to detrimental environmental effects. For finding the QPEdegrading bacteria and promoting the biodegradation of QPE, a series of studies were carried out. ...
Propionatos/metabolismo, Quinoxalinas/metabolismo, Methylobacterium/metabolismo, Herbicidas, Biodegradación Ambiental, Microbiología del Suelo, Hidrolasas/metabolismo, Esterasas/metabolismo, Hidrolasas/análisis, Esterasas/análisis, Methylobacterium/enzimología, Análisis de Secuencia de Proteína, Methylobacterium/genética, Hidrólisis
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Efeito da brimonidina na circulaçäo retrobulbar em pacientes com glaucoma: estudo com doppler colorido
Effect of brimonidine on the retrobulbar circulation in glaucomatous patients: study with color doppler

Silva, Maria Rosa Bet de Moraes; Rollo, Hamilton Almeida; Schellini, Silvana A.
Arq. bras. oftalmol; 64 (4), 2001
Objetivo: Avaliar o efeito do tartarato de brimonidina a 0,2 por cento tópico, ins-tilado de 12/12 horas, na circulaçäo retrobulbar em pacientes portadores de glaucoma. Métodos: Foram estudados os 2 olhos de 16 pacientes portadores de glaucoma primário de ângulo aberto e glaucoma crônico de ângul...
Ultrasonografía Doppler en Color, Quinoxalinas/uso terapéutico, Estudios Prospectivos
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