DNA damage in a solution containing copper(II) ions and ascorbic acid: Effect of the presence of sulfite
Braz. J. Pharm. Sci. (Online); 57 (), 2021
Some antioxidant compounds have a pro-oxidant effect in the presence of transition metal ions, due to the reduction of Mn+ to M(n-1)+ with simultaneous formation of free radicals, which then promote DNA damage. In the present study, we evaluated the pUC19 DNA damage in a solution containing Cu(II) and as...