Results: 5

Impact of HER2 receptor status on axillary nodal burden in patients with non-luminal A invasive ductal breast carcinoma

Rev. méd. Chile; 147 (5), 2019
ABSTRACT Background: Breast cancer (BC) is the most common malignancy in women. Aim: To assess the impact of HER2 status on axillary lymph node (ALN) involvement in patients with invasive ductal carcinoma of no special type (IDC-NST) both at diagnosis and during the 4-year postoperative period. Patien...

Supervivencia en cáncer de mama por subtipo mediante inmunohistoquímica: Un estudio retrospectivo

Gac. méd. Méx; 155 (supl.1), 2019
Resumen Antecedentes: La clasificación del cáncer de mama en subtipos mediante la expresión de receptores hormonales (RH) y del receptor 2 del factor de crecimiento epidérmico humano (HER2) por inmunohistoquímica (IHQ) es una práctica estándar para la toma de decisiones terapéuticas. Objetivo: ...

Características clínicas y pronóstico de pacientes con cáncer de mama HER2 positivo avanzado, en la era antes y después de terapias anti-HER2

Rev. méd. Chile; 146 (10), 2018
Background: HER2+ breast cancer (BC) subtype overexpresses the Human Epidermal growth factor Receptor type-2 (HER2) and is characterized by its aggressiveness and its high sensitivity to monoclonal antibody-based HER2-targeted therapies. Aim: To assess the prognosis and evaluate the impact of novel anti...

Assessment of HER-2 status in invasive breast cancer in Brazil

Summary Objective: To characterize the frequency of HER-2-positive breast cancer in Brazil. Method: In this prospective observational study, we first ascertained the HER-2 status of invasive breast cancer specimens by automated immunohistochemistry (IHC). For specimens classified as 2+ by IHC, we perfo...

Fatores prognósticos em câncer de mama em mulheres pré e pós-menopausa

A incidência crescente, a heterogeneidade e a taxa elevada de mortalidade do câncer de mama, têm estimulado pesquisas com o objetivo de se identificar fatores que facilitam a compreensäo do comportamento biológico nesta neoplasia. Estes fatores podem ser classificados em prognósticos ou preditivos....