Purpose: This study evaluated the protective effect of hesperidin on injury induced by gastric ischemia-reperfusion. Methods: Fifty male Sprague Dawley rats (250–300 g) were divided into five groups: control (C), sham (S), ischemia (I), ischemia-reperfusion (I/R) and hesperidin + ischemia-reperfusion (...
Purpose: To investigate inflammation and cell adhesion molecules in the vagina after ovarian ischemia-reperfusion (IR) injury. Methods: 20 Wistar albino female rats were divided into two groups: control, and IR groups. In IR group, blood flow was restricted for 2 hours for ovarian ischemia. Then, tissues...
Liu, Haiqiong;
Liang, Qian;
Mei, Xiheng;
Li, Hekai;
Yan, Jing;
Long, Man;
Yang, Xili;
Wang, Wei;
Li, Weijie;
Chen, Aihua;
Ling, Yuanna.
Abstract Compound Danshen Dripping Pills (CDDPs) have been used in clinical treatment to protect the heart from ischemia/reperfusion (IR) injury for many years. However, the underlying mechanism implicated in the protective effects remains to be explored. Here, we determined the effects of CDDPs in Sprag...
Ecocardiografía/métodos,
d0013430,
d0172090,
Isquemia/clasificación,
Reperfusión/clasificación,
Corazón/fisiopatología,
Infarto/patología,
Microscopía Electrónica de Transmisión/métodos,
d0275610,
Daño por Reperfusión/clasificación,
Western Blotting/instrumentación
Purpose: Our aim was to investigate protective effects of daidzein treatment on ischemia-reperfusion (I/R) injury-induced ovarian tissue by immunohistochemical techniques. Methods: Thirty Sprague Dawley female rats were categorized into three groups as sham, I/R group, and I/R+daidzein groups. Bloods we...
Introducción: CD38 es una glicoproteína transmembrana de 300 aminoácidos y 45 kDa expresada de forma ubicua en el organismo que cumple importantes funciones en el metabolismo del cofactor NAD+ y en la regulación del movimiento del calcio celular. Uno de los productos enzimáticos de CD38 es el adenos...
RESUMEN Introducción: el infarto agudo de miocardio con elevación del segmento ST como parte del síndrome coronario agudo, es una afección frecuente que cursa con una elevada mortalidad. En los últimos años, las enfermedades cardiovasculares han constituido la primera causa de muerte en Cuba, y en ...
The effects of the aqueous extract of Ilex paraguariensis (Ip)and the flavonoid quercetin were tested during the induction of in vivomyocardial ischemia/ reperfusion in Rattus norvegicus. The antioxidant power of the extract and quercetin were chemically determined. The experimental groups we...
Antioxidantes,
Flavonoides,
Ilex paraguariensis/efectos adversos,
Isquemia/tratamiento farmacológico,
Quercetina/análisis,
Administración Oral,
Infarto del Miocardio/tratamiento farmacológico,
Estrés Oxidativo/efectos de los fármacos,
Ratas,
Reperfusión,
Tés Medicinales/efectos adversos
Purpose:
To investigate the role of peptidyl-prolyl cis/trans isomerase 1 (Pin1) on renal ischemia-reperfusion (I/R) injury and underlying mechanism.
Methods:
By establishing the in vitro and in vivo models of renal I/R, the role of Pin1 was explored by using molecular assays.
Results:
In renal I/R, en...
ABSTRACT Objective: To evaluate the effect of curcumin on renal function, hemodynamics, and renal oxidative profile of rats with chronic kidney disease (CKD) subjected to renal ischemia-reperfusion injury (IRI). Methods: Wistar rats, 250-300 g, distributed in four groups: Sham (n = 5), CKD simulation; ...
Abstract The aim of the present study is to investigate the cardioprotective effects of 18β-glycyrrhetinic acid (18β -GA) against oxidative and histological damage caused by global cerebral ischemia/ reperfusion (I/R) in C57BL/J6 mice. All male mice (n:40) were randomly divided into four groups: (1) s...
