INTRODUCCIÓN: La Enfermedad de Cushing es una de las causas menos prevalentes de hipertensión arterial secundaria (HTA) (0,7 a 2,4 casos por millón de personas), sin embargo conlleva un aumento de la morbi-mortalidad que se relaciona con el tiempo de exposición al exceso de corticoides 6, lo cual rep...
Hipertensión,
Síndrome de Cushing,
Hipersecreción de la Hormona Adrenocorticotrópica Pituitaria (HACT),
Adenoma Hipofisario Secretor de ACTH,
Presión Arterial,
Sistema Hipófiso-Suprarrenal,
Ecuador,
Indicadores de Morbimortalidad,
Factores de Riesgo de Enfermedad Cardiaca,
Prevención de Enfermedades,
Factor Esteroidogénico 1,
Calidad de Vida
ABSTRACT BACKGROUND: Critical diseases usually cause hypercortisolemia via activation of the hypothalamic-pituitary-adrenal axis. OBJECTIVES: To investigate the relationship between serum total cortisol level and mortality among coronavirus disease 2019 (COVID-19) patients in the intensive care unit (I...
Abstract After a stressful event, adaptative mechanisms are carried out to support vital functions. Hypothalamic-pituitary-adrenal axis plays a key role in stress response regulating metabolism, cardiovascular function and immune system. This review addresses pathophysiological changes of the adrenal axi...
Hypopituitarism after moderate or severe traumatic brain injury (TBI) is usually underdiagnosed and therefore undertreated. Its course can be divided in an acute phase during the first 14 days after TBI with 50 to 80% risk of hypopituitarism, and a chronic phase, beginning three months after the event, w...
ABSTRACT Objective To investigate whether a combination of the low-dose (1 µg) adrenocorticotropin (ACTH) stimulation test and glucagon stimulation test (GST) could overcome the problem of equivocal results with the GST or ACTH test alone in patients with pituitary disorders. Subjects and methods Th...
ABSTRACT Objective The insulin tolerance test (ITT) has been accepted as the gold standard test for assessing the integrity of the growth hormone (GH) - insulin-like growth factor (IGF-1) axis and the hypothalamic-pituitary-adrenal (HPA) axis. The goal of the test is to achieve clinical and biochemical...
Automonitorización de la Glucosa Sanguínea,
Prueba de Tolerancia a la Glucosa/efectos adversos,
Prueba de Tolerancia a la Glucosa/métodos,
Hormona de Crecimiento Humana/sangre,
Hidrocortisona/sangre,
Hipoglucemia/sangre,
Hipoglucemia/diagnóstico,
Hipoglucemia/metabolismo,
Hipoglucemiantes/administración & dosificación,
Sistema Hipotálamo-Hipofisario/metabolismo,
Insulina/administración & dosificación,
Factor I del Crecimiento Similar a la Insulina/análisis,
Sistema Hipófiso-Suprarrenal/metabolismo,
Estudios Retrospectivos
Opioids are the main group of pharmacological agents used during the perioperative period and provide a sedative and analgesic component. The observations of opioid consumption in West Europe indicate that this group of drugs is widely used in chronic noncancer pain therapy. Nearly 20 years ago, the firs...
Resumen El síndrome de ovarios poliquísticos es la enfermedad endocrina más frecuente en la edad reproductiva; se caracteriza por alteraciones menstruales, hiperandrogenismo clínico o bioquímico e identificación ultrasonográfica de quistes ováricos. Las alteraciones neuroendocrinas y metabólicas...
In view of the fact that cancer is considered a chronic disease that can interfere with hormonal homeostasis by means of cytokines, we hypothesized that, even at early stages, mammary carcinoma is able to alter the balance of the hypothalamic-pituitary-thyroid and hypothalamic-pituitary-adrenal axes. To ...
Summary Introduction: Oral corticosteroids (OCS) are a mainstay of treatment for asthma exacerbations, and short-term OCS courses were generally considered to be safe. Nevertheless, frequent short-term OCS courses could lead to hypothalamic-pituitary-adrenal (HPA) axis dysfunction. Our study aimed at in...
Administración por Inhalación,
Administración Oral,
Corticoesteroides/administración & dosificación,
Corticoesteroides/efectos adversos,
Insuficiencia Suprarrenal/inducido químicamente,
Insuficiencia Suprarrenal/fisiopatología,
Asma/tratamiento farmacológico,
Asma/fisiopatología,
Progresión de la Enfermedad,
Hidrocortisona/sangre,
Sistema Hipotálamo-Hipofisario/efectos de los fármacos,
Sistema Hipotálamo-Hipofisario/fisiopatología,
Mediciones Luminiscentes,
Sistema Hipófiso-Suprarrenal/efectos de los fármacos,
Sistema Hipófiso-Suprarrenal/fisiopatología,
Estudios Prospectivos,
Valores de Referencia,
Factores de Riesgo,
Estadísticas no Paramétricas,
Factores de Tiempo
