Results: 8

In vivo Gonadoprotective Effects of Myricetin on Cisplatin- Induced Testicular Damage via Suppression of TLR4/NF-kB Inflammation Pathway and Heat-Shock Response

Int. j. morphol; 41 (6), 2023
SUMMARY: The aim of this study is to reveal the gonadoprotective effects of myricetin (MYC), which has many biological properties, on cisplatin (CP)-induced testicular damage in rats. For this purpose, 40 male Wistar albino rats were divided into 4 groups as Control (group given no treatment), MYC (group...

Quercetin Inhibits ROS-p53-Bax-caspase-3 axis of apoptosis and augments gonadotropin and testicular hormones in chronic unpredictable stress-Induced testis injury

Int. j. morphol; 39 (3), 2021
SUMMARY: A large body of evidence supports the protective role of the flavonol antioxidant compound quercetin in mammals. We tested the hypothesis that quercetin can protect against the hypothalamus-pituitary-gonadal (HPG) axis defect like a reduction in gonadotropins and testicular hormones and abnormal...

Effects of ketoprofen in spermatogenesis of mice exposed to continuos hypobaric hypoxia

Int. j. morphol; 37 (4), 2019
Hypoxia hypobaric (HH) can cause alterations at testicular level, with temperature increase, intrascrotal alteration and deterioration of spermatogenesis. Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ketoprofen have anti-angiogenic properties, and can decrease testicular abnormalities. The objec...

Role of JNK and ERK1/2 MAPK signaling pathway in testicular injury of rats induced by di-N-butyl-phthalate (DBP)

Biol. Res; 52 (), 2019
BACKGROUND: Di-N-butyl-phthalate (DBP) is an endocrine disrupting substance. We investigated the adverse effect of DBP on testis of male rat and reveal its potential mechanism of MAPK signaling pathway involved this effect in vivo and in vitro. Gonadal hormone, sperm quality, morphological change and the...

Traumatismo testicular cerrado
Traumatic testis

Rev. chil. urol; 51 (2), 1988
Presentamos una serie de pacientes, en su mayoría adultos jóvenes (85%) con traumatismo testicular. El 25% fué por accidentes deportivos; agresiones (20%), caídas a horcajadas (20%), contusión directa (20%) y coz de caballo (15%). No se dispuso de sonografías, el criterio diagnóstico fue clínico ...