Abstract The human respiratory syncytial virus (hRSV) is the most common cause of severe lower respiratory tract diseases in young children worldwide, leading to a high number of hospitalizations and significant expenditures for health systems. Neutrophils are massively recruited to the lung tissue of pa...
Introdução: As redes extracelulares de neutrófilos (NETs) são apontadas como um
dos mecanismos relevantes na patogênese da periodontite e artrite reumatoide (AR).
No entanto, permanece pouco compreendido a participação das NETs como
mecanismo de ligação entre as duas doenças. Objetivos: 1) Inve...
ABSTRACT Neutrophils play an important role in immune defence against several pathogens. These cells actively participate in the innate immune response through different functions, such as chemotaxis, phagocytosis, oxidative burst and degranulation, which have been widely studied. However, in the last fe...
Abstract We sought to compare the characteristics and clinical significance of neutrophil extracellular traps in gingival samples from patients with periodontitis and those with gingivitis. The clinical indexes of gingival samples from patients with periodontitis and gingivitis were measured; the express...
Actinas/análisis,
Western Blotting,
Estudios de Casos y Controles,
Electroforesis en Gel de Agar,
Trampas Extracelulares,
Gingivitis/patología,
Interleucina-8/análisis,
Metaloproteinasa 9 de la Matriz/análisis,
Persona de Mediana Edad,
Neutrófilos/patología,
Índice Periodontal,
Periodontitis/patología,
ARN/análisis,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Valores de Referencia,
Receptor Toll-Like 8/análisis,
Factor de Necrosis Tumoral alfa/análisis
ABSTRACT Neutrophil extracellular traps (NETs) were described more than one decade ago, but recently, the interest in these structures has increased due to their involvement in cancer progression, cancer-related thrombosis, and development of metastasis. This protumoral role of NETs strengthens their pot...
Somando a maioria dos leucócitos presentes na corrente sanguínea, os neutrófilos são células polimorfonucleares e especializadas no combate a infecções através da fagocitose do patógeno e liberação de seus conteúdos granulares. Também são capazes de liberar armadilhas extracelulares (neutro...
Apoptosis,
Trampas Extracelulares,
Circulación Sanguínea,
Autoinmunidad,
Anticuerpos,
Enfermedades Autoinmunes,
Fagocitosis,
Neutrófilos,
Leucocitos,
Proteínas,
Noxas
Además de ser elementos clave en la hemostasia y trombosis, las plaquetas tienen un rol preponderante en la respuesta inflamatoria e inmune asociada con su capacidad para reconocer patógenos a través de la expresión de los receptores tipo Toll, la secreción de una amplia variedad de citoquinas, quem...
La alergia es una reacción de hipersensibilidad iniciada por mecanismos inmunológicos y mediada por anticuerpos o células; se desencadena en individuos previamente sensibilizados a un alérgeno. En la mayoría de los casos, el anticuerpo responsable de la reacción alérgica es la inmunoglobulina E (I...
