BACKGROUND: Histopathological analysis of tissue samples is an ancillary complementary diagnostic tool in tuberculosis (TB) with variable sensitivity and specificity according to different clinical settings. We evaluated the spectrum of histological findings, their diagnostic sensitivity, diagnostic util...
Biopsia/métodos,
Chile,
Granuloma/diagnóstico,
Granuloma/microbiología,
Granuloma/patología,
Mycobacterium tuberculosis/genética,
Mycobacterium tuberculosis/aislamiento & purificación,
Estudios Retrospectivos,
Sensibilidad y Especificidad,
Tuberculosis/diagnóstico,
Tuberculosis/microbiología,
Tuberculosis/patología
Infectious diseases significantly contribute to global morbidity and mortality, highlighting the critical need for robust disease surveillance systems. The rapid and accurate identification of infection hotspots is crucial for effective disease control and eliminating vector reservoirs. Traditional metho...
Abstract Recently, the world has coped with the challenge of the novel SARS-CoV-2 rapid spreading, causing COVID-19. This scenario has overburdened health systems, forced social isolation, and interrupted some services, changing the way how health assistance is provided. The management of chronic infecti...
Abstract Tuberculosis treatment consists of a drug combination, where isoniazid is the core drug and alcoholism is a factor highly related to poor patient compliance with the therapy. CYP2E1 is an enzyme involved both in the metabolism of ethanol and in the formation of hepatotoxic compounds during the m...
HIV/AIDS, tuberculose, malária e as doenças tropicais negligenciadas representam uma grande preocupação em Saúde em muitas regiões do mundo. Os fármacos disponíveis para o tratamento apresentam diversos problemas, tais como toxicidade e resistência ao parasita. Mesmo com esse triste panorama, o ...
Dendrímeros/efectos adversos,
Malaria/patología,
Tuberculosis/patología,
Profármacos/análisis,
Antimaláricos/análisis,
Apoyo a la Formación Profesional/clasificación,
Acciones Farmacológicas,
Enfermedades Desatendidas/complicaciones,
Espectroscopía de Resonancia Magnética/métodos,
Espectrometría de Masas/métodos,
VIH/patogenicidad,
Preparaciones Farmacéuticas/análisis
Tuberculosis is an infectious disease that involves any organ. However, the primary pituitary tuberculosis is an extremely rare disease. Intracranial tuberculomas account for 0.15-5% of intracranial space-occupying lesions, of which, pituitary as the primary site is unusual, and easily misdiagnosed as pi...
A case of probable coronary arteritis in a young girl who died suddenly and unexpectedly is presented. The histologic presentation of the disorder is discussed, especially the differential diagnosis of arteritis of the coronary arteries with an emphasis on tuberculosis (TB). TB myocarditis with or withou...
Las enfermedades granulomatosas incluyen una amplia gama de enfermedades. Sin embargo, en la práctica clínica, muchos casos de enfermedad granulomatosa permanecen sin etiología después del examen histológico. Nuestro objetivo fue determinar, a partir de las biopsias de pulmón, pleura y ganglios lin...
Enfermedades Pulmonares/diagnóstico,
Enfermedades Pulmonares/patología,
Granuloma/diagnóstico,
Granuloma/patología,
Estudios Retrospectivos,
Tuberculosis/diagnóstico,
Tuberculosis/patología,
Sarcoidosis/diagnóstico,
Sarcoidosis/patología,
Diagnóstico Diferencial,
Biopsia,
Estudios de Seguimiento
Las cepas del bacilo tuberculoso con farmacorresistencia (TB-DR) son más difíciles de tratar que las
farmacosensibles y amenazan el progreso mundial hacia los objetivos establecidos por la Estrategia Fin de
la TB, de la Organización Mundial de la Salud (OMS). Por lo tanto, existe una necesidad imperio...
