Abstract Background Cardiotoxicity is the main complication related to cancer therapy. Studies indicate that global longitudinal strain is an early detector of subclinical dysfunction of the left ventricle, preceding the decline in ejection fraction (EF). However, the reproducibility of such methodolog...
Fundamento: A cardiotoxicidade induzida por quimioterapia (CiC) é uma complicação importante entre os pacientes que recebem antraciclinas. Biomarcadores e parâmetros de imagem têm sido estudados por sua capacidade de identificar pacientes com risco de desenvolver essa complicação. O strain longitu...
Background: The combination of doxorubicin (DOX) with paclitaxel (PTX) effectively treats breast cancer (BC). However, DOX-associated cardiotoxicity (CTX) is aggravated by the use of PTX. Consensus is lacking about which drug sequence involves the most CTX. Objectives: To evaluate whether DOX followed by...
Hydrocephalus is a major concern in neurocysticercosis (NCC), and its management is
more challenging than that of hydrocephalus caused by other etiologies. Even though
albendazole is a well-established drug for the treatment of NCC, the death of the
parasites may worsen the clinical symptoms and eventual...
Abstract Background: Anthracycline generates progressive left ventricular dysfunction associated with a poor prognosis. Objectives: The purpose of this study was to evaluate whether layer-specific strain analysis could assess the subclinical left ventricular dysfunction after exposure to anthracyclin...
Abstract Background: Cardiotoxicity is an important side effect of trastuzumab therapy and cardiac surveillance is recommended. Objectives: The aim of our study was to prospectively assess baseline patients' characteristics, level of N-terminal pro-brain natriuretic peptide (NT-proBNP) and echocardiogr...
La presión barométrica y la presión parcial de O2 disminuyen con la altura y la hipoxia hipobárica generada es la responsable de las enfermedades relacionadas con la altitud y del deterioro del rendimiento deportivo. Las adaptaciones fisiológicas a la altura son múltiples y contribuyen a la alterac...
Comparar, através de estudo prospectivo e randomizado, os resultados do emprego da estreptoquinase (SK) e do 5-TPA por via venosa, no infarto agudo do miocárdio (IAM). Cem pacientes internado consecutivamente com diagnóstico de IAM com menos de seis horas de evoluçäo, receberam alternadamente, por v...
