Nhampossa, Tacilta;
Fernández-Luis, Sheila;
Fuente-Soro, Laura;
Bernardo, Edson;
Nhacolo, Arsénio;
Orvalho, Augusto;
Nhacolo, Ariel;
Sacoor, Charfudin;
Saura-Lázaro, Anna;
Lopez-Varela, Elisa;
Naniche, Denise.
prevalence and a long history of migration. To optimize HIV care, we sought to assess how caregiver's mobility impacts children living with HIV (CLHIV)´s continuation in HIV care and to explore the strategies used by caregivers to maintain their CLHIV on antiretroviral treatment (ART). A clinic-based cr...
Teasdale, Chloe A;
Brittain, Kirsty;
Zerbe, Allison;
Mellins, Claude Ann;
Falcao, Joana;
Couto, Aleny;
De Gusmao, Eduarda Pimentel;
Vitale, Mirriah;
Kapogiannis, Bill;
Simione, Teresa Beatriz;
Myer, Landon;
Mantell, Joanne;
Desmond, Christopher;
Abrams, Elaine J.
Background: Adolescents living with HIV (ALHIV) 15-19 years of age are a growing proportion of all people living with HIV globally and the population includes adolescents with vertically acquired HIV (AVH) and behaviorally acquired HIV (ABH).
Methods: We conducted a survey to measure sociodemographic ch...
Anti-Retroviral Agents/therapeutic use,
Condoms,
Educational Status,
HIV Infections/epidemiology,
HIV Infections/physiopathology,
HIV Infections/transmission,
HIV-1/pathogenicity,
Medical History Taking/statistics & numerical data,
Medication Adherence/statistics & numerical data,
Sexual Behavior/statistics & numerical data,
Mozambique/epidemiology
Augusto, Ângelo do Rosário;
Nnaemeka, Nnaemeka C;
Kohatsu, Luciana;
Sousa, Leonardo de;
Maueia, Cremildo;
Hara, Cristina;
Mula, Flora;
Cuamba, Gércio;
Chelene, Imelda;
Langa, Zainabo;
Lohman, Nathaniel;
Faife, Flávio;
Giles, Denise;
Sabonete, Acácio José;
Gudo, Eduardo Samo;
Jani, Ilesh;
Parekh, Bharat S.
Effective implementation of the national Human Immunodeficiency Virus (HIV) programs require monitoring the HIV epidemic trends to identify programmatic successes, challenges, and needed improvements. HIV prevalence estimates, defined as the percentage of a population affected by HIV, are calculated by t...
This study evaluated a National External Quality Scheme Program for early infant diagnosis of HIV. Fourteen laboratory technicians participated, and nine testing panel cycles were sent between 2011 and 2014. The response rate was 100% for the first eight panels, and the number of technicians with a test ...
Introduction: Viral load testing is essential to manage HIV disease, especially in infants and children. Early infant diagnosis (EID) is performed using nucleic-acid testing in children under 18 months. Resource-limited health systems face severe challenges to scale-up both viral load and EID to unpreced...
HIV Infections/diagnosis,
HIV Infections/virology,
HIV-1/genetics,
HIV-1/isolation & purification,
HIV-1/physiology,
Infant, Newborn, Diseases/diagnosis,
Infant, Newborn, Diseases/virology,
Mozambique,
Sensitivity and Specificity,
Prospective Studies,
Viral Load/methods,
Viremia/diagnosis,
Viremia/virology
Philips, Andrew N;
Cambiano, Valentina;
Nakagawa, Fumiyo;
Matharu, Loveleen Bansi;
Wilson, David;
Jani, Ilesh;
Apollo, Tsitsi;
Sculpher, Mark;
Hallett, Timothy;
Kerr, Cliff 2 7;
Ooterhout, Joep J van;
Eaton, Jeffrey W;
Estill, Janne 10 11;
Williams, Brian;
Doi, Naoko;
Cowan, Frances;
Keiser, Olivia;
Ford, Deborah;
Hatzold, Karin;
Barnabas, Ruanne;
Ayles, Helen;
Rath, Gesine Meyer;
Nelson, Lisa;
Johnson, Cheryl;
Baggaley, Rachel;
Fakoya, Ade;
Jahn, Andreas;
Revill, Paul.
Introduction: As prevalence of undiagnosed HIV declines, it is unclear whether testing programmes will be cost-effective. To guide their HIV testing programmes, countries require appropriate metrics that can be measured. The cost-per-diagnosis is potentially a useful metric.
Methods: We simulated a serie...
Africa, Southern,
Circumcision, Male,
d0000829220,
Cost-Benefit Analysis,
HIV Infections/diagnosis,
HIV Infections/epidemiology,
HIV-1,
Mass Screening/economics,
Poverty,
Pregnancy,
Risk Factors,
Sex Workers
Cunha, Lina;
Carrilho, Carla;
Bhatt, Nilesh;
Loforte, Michella;
Maueia, Cremildo;
Fernandes, Fabíola;
Guisseve, Assucena;
Mbofana, Francisco;
Maibaze, Fatima;
Mondlane, Liana;
Ismail, Muhammad;
Dimande, Luzmira;
Machatine, Sheila;
Lunet, Nuno;
Liu, YuTsueng;
Samo Gudo, Eduardo;
Pineau, Pascal.
Mozambique had been ranked among the countries with the highest
global incidence of HCC with chronic hepatitis B infection and high exposure to aflatoxin-B1
(AFB1) being major risk factors. Indeed, HCC remains one of the most frequent cancer in Maputo.
On the other hand, Mozambique has a high prevalence ...
Mozambique,
HIV,
Hepatitis B, Chronic,
Hepatitis B,
HIV-1,
Hepatitis Antibodies,
Hepatitis C Antibodies,
HIV Infections,
Hepatitis C,
Immunity
Chissumba, Raquel Matavele;
Luciano, Abílio;
Namalango, Eduardo;
Bauer, Asli;
Bhatt, Nilesh;
Wharen, Britta;
Nilsson, Charlotta;
Geldmacher, Christof;
Scarlatti, Gabriella;
Jani, Ilesh;
Kastens, Luc.
Little is known about regulatory CD4 T cells (Tregs) in the context of HIV vaccines. Tregs can be differentiated into resting (FoxP3+CD45RA+ - rTregs), activated (FoxP3HighCD45RA- - aTregs) and memory (FoxP3LowCD45RA- - mTregs). Tregs, as CD4 T cells, are also frequent targets for HIV infection. We studi...
AIDS Vaccines/immunology,
Antibodies, Neutralizing/immunology,
CD4 Lymphocyte Count,
Cytokines/biosynthesis,
HIV Antibodies/immunology,
HIV Infections/prevention & control,
HIV Infections/virology,
HIV-1/immunology,
HIV-1/genetics,
Mozambique,
CD8-Positive T-Lymphocytes/immunology,
T-Lymphocytes, Regulatory/metabolism,
Vaccines, DNA/immunology,
Vaccines, DNA/genetics
Megg, Bindiya;
Vojnov, Lara;
Mabunda, Nédio;
Vubil, Adolfo;
Zitha, Alcina;
Tobaiwa, Ocean;
Mudenyanga, Chishamiso;
Mutsaka, Dadirayi;
Bollinger, Timothy;
Loquiha, Osvaldo;
Pete, Trevor F;
Jan, Ilesh V.
Worldwide only 43% of infants infected with HIV have access to antiretroviral treatment (ART). Despite significant global efforts to expand access to paediatric treatment, coverage lags behind adult ART and may not reach the 90-90-90 goals by 2020 as set by UNAIDS [2]. Resolving this paediatric ART gap i...
Rupérez, María;
Julian, Marc Noguera;
González, Raquel;
Maculuve, Sonia;
Bellido, Rocío;
Vala, Anifa;
Rodríguez, Cristina;
Sevene, Esperança;
Paredes, Roger;
Menéndez, Clara.
Background: Few data on HIV resistance in pregnancy are available from Mozambique, one of the countries with the highest HIV toll worldwide. Understanding the patterns of HIV drug resistance in pregnant women might help in tailoring optimal regimens for prevention of mother to child transmission of HIV (...
Anti-HIV Agents/administration & dosage,
CD4 Lymphocyte Count/methods,
Drug Resistance, Viral,
HIV Infections/drug therapy,
Drug Resistance, Viral/drug effects,
Infectious Disease Transmission, Vertical/prevention & control,
Pregnancy Complications, Infectious/drug therapy,
Mozambique,
Prenatal Care/methods,
HIV-1/chemistry
