Mozambique has a generalized HIV epidemic, among pregnant women, HIV prevalence is estimated at 15.8% with a vertical transmission rate of 14%, more than double global targets. We evaluate electronic national health information system (SIS-MA) performance to verify if the data flow procedures met its obj...
HIV Infections/prevention & control,
Infectious Disease Transmission, Vertical/prevention & control,
Pregnancy Complications, Infectious/virology,
Feline Acquired Immunodeficiency Syndrome/prevention & control,
Mozambique,
Feline Acquired Immunodeficiency Syndrome/transmission,
HIV Infections/transmission,
Population Surveillance,
Pregnancy,
Surveys and Questionnaires
Alonso, Selena;
Vudal, Marta;
Olalla, Gemma Ruiz;
Gonzelez, Raquel;
Manaca, M Nelia;
Jairoce, Chenjerai;
Balcells, Reyes;
Vala, Anifa;
Ruperez, María;
Soro, Laura Fuente;
Cova, Marta;
Angov, Evelina;
Nhacolo, Arsenio;
Sevene, Esperança;
Aponte, John J;
Macete, Eusebio;
Dobano, Carlota;
Moncunil, Gemma.
Transplacental transfer of antibodies is essential for conferring protection in newborns against infectious diseases. We assessed the impact of different factors, including gestational age and maternal infections such as HIV and malaria, on the efficiency of cord blood levels and placental transfer of Ig...
Antibodies/immunology,
Antigens/immunology,
Antiretroviral Therapy, Highly Active,
Fetal Blood/immunology,
HIV Infections/therapy,
HIV Infections/epidemiology,
HIV Infections/immunology,
HIV Infections/virology,
Immunity, Maternally-Acquired,
Immunoglobulin G/immunology,
Maternal-Fetal Exchange/immunology,
Placenta/metabolism,
Pregnancy,
Carrier Proteins,
Sex Factors,
Vaccines/immunology
Background: Technological advances and high throughput biological assays can facilitate discovery science in biobanks from population cohorts, including pregnant women. Biological pathways associated with health outcomes differ depending on geography, and high-income country data may not generalise to lo...
O ganho de peso gestacional excessivo ou insuficiente é considerado como um factor de risco para a gestante e ao feto podendo ser influenciado por vários factores dentre eles: sócio-demográficos, clínicos, estilos de vida e obstétricos. Este estudo tinha como objectivo principal determinar o ganho ...
Sevene, espranca;
Shama, sumedha;
Munguambe, khatia;
Sacaor, charfudin;
Vala, anifa;
Macuacua, saliesio;
Boane, helena;
Arsenio, j mark;
Augusto, orvalho;
Bique, cassimo;
Bone, jeffrey;
Dusmmuir, dustin T;
Lee, tang;
Li, jing;
Macte, eusebio;
Singer, joel;
Wang, hannh l;
Payne, beth a;
Sidat, mohision;
Shennan, andrew h;
Thavana, carssimo;
Tu, domena k;
Vidlev, marianne;
Buhutta, zulfiquar;
Magge, laura a;
Dedelsezen, peter van.
Objectives: Pregnancy hypertension is the third leading cause of maternal mortality in Mozambique and contributes significantly to fetal and neonatal mortality. The objective of this trial was to assess whether task-sharing care might reduce adverse pregnancy outcomes related to delays in triage, transpo...
Hypertension, Pregnancy-Induced/mortality,
Pregnant Women/ethnology,
Pre-Eclampsia/therapy,
Costs and Cost Analysis,
Mozambique/epidemiology,
Pre-Eclampsia/mortality,
Infant Mortality,
Community Health Workers/organization & administration,
Residence Characteristics/statistics & numerical data,
Pregnancy,
Prenatal Care,
Hypertension, Pregnancy-Induced
Cumbane, Victória;
Imbach, Michelle;
Matavele, Raquel;
Macicame, ivalda;
Eller, Leigh;
Lawlor, john;
Milazzo, Mark;
Li, Qun;
Crowell, Trevor;
Mutombene, Mirna;
Guiliche, onelia;
Viegas, edna;
Nwoga, chiaka;
Yates, Adam;
Michael, Nelson;
Robb, Merlin;
Polyak, Christina S;
Jani, ilesh v;
Bhatt, nilesh.
n many African countries, laboratory reference values are not established for the local
healthy adult population. In Mozambique, reference values are known for young adults (18-
24yo) but not yet established for a wider age range. Our study aimed to establish hematological, biochemical and immunological ...
Orvalho, Augusto;
Stergachis, Andy;
Dellicour, Stephanie;
Tinto, Halidou;
Valá, Anifa;
Ruperez, Maria;
Macete, Eusébio;
Nakanabo-Diallo, Seydou;
Kazienga, Adama;
Valéa, Innocent;
d'Alessandro, Umberto;
Kuile, Feiko O Ter;
S Calip, Gregory;
Ouma, peter;
Desai, Meghna;
Sevene, Esperança.
While there is increasing evidence on the safety of artemisinin-based combination therapy (ACT) for the case management of malaria in early pregnancy, little is known about the association between exposure to ACT during the first trimester and the effect on fetal growth. Data were analysed from prospecti...
Combined Modality Therapy,
Artemisinins,
Antimalarials,
Malaria,
Pregnancy,
Pregnancy Trimester, First,
Infant, Small for Gestational Age,
Infant, Low Birth Weight
A fístula obstétrica continua a ser um problema de saúde comum em países de baixa e média renda,
apesar das tendências de aumento dos partos institucionais nesses países. As circunstâncias socio-comportamentais
em que a fístula ocorre, assim como suas consequências, são pouco documentadas, pri...
Delivery of Health Care/standards,
Delivery, Obstetric/standards,
Health Facilities,
Health Knowledge, Attitudes, Practice,
Middle Aged,
Health Services Accessibility,
Mozambique/epidemiology,
Obstetric Labor Complications/prevention & control,
Patient Acceptance of Health Care/psychology,
Postpartum Period/psychology,
Pregnancy,
Prenatal Care/psychology,
Vesicovaginal Fistula/epidemiology,
Vesicovaginal Fistula/surgery
Menéndez, clara;
Quintó, llorenç;
Castillo, paola;
Fernandes, fabiola;
Carrilho, carla;
Ismail, mamudo r;
Lorenzoni, cesaltina;
Hurtado, juan carlos;
Rakislova, natalia;
Munguambe, khátia;
Moraleda, cinta;
Maixenchs, maria;
Macete, eusebio;
Mandomando, inacio;
Martínez, miguel, j;
Alonso, pedro, j;
Bassat, quique;
Ordi, jaume.
Background
Although an increasing number of pregnant women in resource-limited areas deliver in health-care facilities, maternal mortality remains high in these settings. Inadequate diagnosis and management of common life-threatening conditions is an important determinant of maternal mortality. We analys...
Fonseca, ana maria;
Raquel, gonzález;
Bardaji, açucene;
Rupérez, maria;
Llorenç, quintó;
Pau, cisteró;
Gupta, himanshu;
Hegewisch, taylor;
Brew, joe;
Dobanõ, carlota;
Aponte, Joao j;
Menendez, Clara;
Mayor, alfredo;
Jairoce, chenjerai;
Nhacalo, arśenio;
Sevene, esperança;
Machete, eusébio;
Vala, Anifa;
Savour, charfudin;
Adam, nicaise tuikue;
Massougbodji, achille;
Koriuuki, simon;
Puma, pedro;
Lopez, marta.
Pregnant women constitute a promising sentinel group for continuous monitoring of malaria transmission. To identify antibody signatures of recent Plasmodium falciparum exposure during pregnancy, we dissected IgG responses against VAR2CSA, the parasite antigen that mediates placental sequestration. We use...
