Results: 35

Whole genome analyses of DS-1-like Rotavirus A strains detected in children with acute diarrhoea in southern Mozambique suggest several reassortment events

Infect. gent. evol; 69 (), 2019
Rotavirus (RV) is an important enteric pathogen in the young of many mammalian and avian species. The virus belongs to the Reoviridae family and contains an 11-segmented double-stranded RNA (dsRNA) genome. The dsRNA segments encode six structural (VP1–4, 6 and 7) and six non-structural (NSP1–5/6) pro...

Early impact of rotavirus vaccination in children less than five years of age in Mozambique

Vaccine; 36 (47), 2018
Mozambique introduced rotavirus vaccine (Rotarix, GSK Biologicals) in the National Immunization Program in September 2015 with the objective of reducing the burden of total diarrheal disease and specifically severe rotavirus disease. This study aimed to evaluate the early impact of rotavirus vaccine in r...

The role of HIV infection in the etiology and epidemiology of diarrheal disease among children aged 0–59 months in Manhiça District, Rural Mozambique

Int. j. infect. dis; 73 (4), 2018
The Global Enteric Multicenter Study enrolled children with moderate-to-severe diarrhea (MSD) and less-severe diarrhea (LSD) between December 2007 and November 2012. One to three controls for MSD cases and one per LSD case were enrolled and matched by age, sex, and neighborhood. All children were tested ...

Epidemiologia e factores associados a diarreia aguda por norovirus em crianças menores de cinco anos de idade hospitalizadas entre 2014 e 2015: dados do sistema vigilancia nacional de diarreia aguda ViNaDia, Moçambique

Em Maio de 2014 foi implementada pelo INS, uma vigilância nacional de diarreia aguda (ViNaDiA) cujo foco era a vigilância para o rotavírus. Embora o Norovírus (NoV) seja uma importante causa de diarreia em crianças e adultos, existem poucos estudos publicados em Moçambique sobre o papel d...

Relação entre a ocorrencia de cryptospoidium SPP e cystoisospora belli com o estadio da infecção por HIV, em pacientes com diarreia internados nos serviços de medicina interna, HCM (Março de 2016 - Março de 2017)

As Infecções por Cryptosporidium spp e Cystoisospora belli são causas importantes de diarréia em pacientes com VIH (Vírus de Imunodeficiência humana). No entanto, informações relativas a estes dois parasitas são escassas em muitos países africanos, incluindo Moçambique. Objectivos...

Frequencia e caracterização dos genótipos de rotavirus do grupo A em crianças de 0 a 59 meses de idade, atendidas com diarreeia aguda na pediatria do Hospital Central de Nampula, 2015

A doença diarreica na infância constitui um importante problema de saúde pública em Moçambique. A infecção pelo Rotavirus é a uma das causas mais comum de diarreia aguda grave a nível mundial, sendo a diarreia terceira causa de morbi-mortalidade infantil na maioria d...

Association between Precipitation and Diarrheal Disease in Mozambique

Diarrheal diseases are a leading cause of morbidity and mortality in Africa. Although research documents the magnitude and pattern of diarrheal diseases are associated with weather in particular locations, there is limited quantification of this association in sub-Saharan Africa and no studies conducted ...

Feasibility of using regional sentinel surveillance to monitor the rotavirus vaccine impact, effectiveness and intussusception incidence in the African Region

Vaccine; 35 (13), 2017
The 9th African rotavirus symposium was held in Maputo, Mozambique from the 8th to 10th of December 2015, including a total of 101 delegates from 17 countries, 15 of which were African countries. This forum brought together participants with various expertise including scientists, clinicians, immunizatio...

Severe malnutrition among children under the age of 5 years admitted to a rural district hospital in southern Mozambique

Public health nutr; 16 (9), 2013
Objective: To describe the burden, clinical characteristics and prognostic factors of severe malnutrition in children under the age of 5 years. Design: Retrospective study of hospital-based data systematically collected from January 2001 to December 2010. Setting: Rural Mozambican district hospital. Subj...

Prevalência e caracterização molecular de rotavírus em crianças menores de 5 anos com diarreia aguda no distrito de chókwè-moçambique

A diarréia é uma importante causa de morbidade e mortalidade em todas as regiões do mundo e entre todas as idades, ainda pouco se sabe sobre a fracção de episódios de diarréia e óbitos de cada patógeno. Os rotavírus (RVs) foram designados como principal causa de doença diarréica e desihidrata...