Results: 39

Molecular epidemiology of rotavirus a strains pre- and post-vaccine (rotarix®) introduction in mozambique, 2012–2019: emergence of genotypes g3p[4] and g3p[8]

PloS pathog; 9 (), 2020
Group A rotavirus (RVA) remains the most important etiological agent associated with severe acute diarrhea in children. Rotarix® monovalent vaccine was introduced into Mozambique’s Expanded Program on Immunization in September 2015. In the present study, we report the diversity and prevalence of rotav...

Intestinal protozoan infections among children 0-168 months with diarrhea in Mozambique: June 2014 - January 2018

Plos negl. trop. dis; 14 (4), 2020
Intestinal parasites such as Cryptosporidium spp., Giardia lamblia and Entamoeba histolytica can cause severe diarrhea, especially among children in developing countries. This study aims to determine the frequency of Cryptosporidium spp., Giardia lamblia and Entamoeba histolytica in children with diarrhe...

Risk factors for death among children 0-59 months of age with moderate-to-severe diarrhea in Manhiça district, southern Mozambique

BMC infect. dis; 19 (1), 2019
In spite of very significant decreasing trends in the last three decades, childhood mortality remains unacceptably high globally, with 5.6 million children dying every year before reaching their 5th birthday, the majority of which in low and middle-income countries (LMIC) [1]. Diarrheal diseases still re...

Whole genome analyses of DS-1-like Rotavirus A strains detected in children with acute diarrhoea in southern Mozambique suggest several reassortment events

Infect. gent. evol; 69 (), 2019
Rotavirus (RV) is an important enteric pathogen in the young of many mammalian and avian species. The virus belongs to the Reoviridae family and contains an 11-segmented double-stranded RNA (dsRNA) genome. The dsRNA segments encode six structural (VP1–4, 6 and 7) and six non-structural (NSP1–5/6) pro...

Early impact of rotavirus vaccination in children less than five years of age in Mozambique

Vaccine; 36 (47), 2018
Mozambique introduced rotavirus vaccine (Rotarix, GSK Biologicals) in the National Immunization Program in September 2015 with the objective of reducing the burden of total diarrheal disease and specifically severe rotavirus disease. This study aimed to evaluate the early impact of rotavirus vaccine in r...

The role of HIV infection in the etiology and epidemiology of diarrheal disease among children aged 0–59 months in Manhiça District, Rural Mozambique

Int. j. infect. dis; 73 (4), 2018
The Global Enteric Multicenter Study enrolled children with moderate-to-severe diarrhea (MSD) and less-severe diarrhea (LSD) between December 2007 and November 2012. One to three controls for MSD cases and one per LSD case were enrolled and matched by age, sex, and neighborhood. All children were tested ...

Epidemiologia e factores associados a diarreia aguda por norovirus em crianças menores de cinco anos de idade hospitalizadas entre 2014 e 2015: dados do sistema vigilancia nacional de diarreia aguda ViNaDia, Moçambique

Em Maio de 2014 foi implementada pelo INS, uma vigilância nacional de diarreia aguda (ViNaDiA) cujo foco era a vigilância para o rotavírus. Embora o Norovírus (NoV) seja uma importante causa de diarreia em crianças e adultos, existem poucos estudos publicados em Moçambique sobre o papel d...

Relação entre a ocorrencia de cryptospoidium SPP e cystoisospora belli com o estadio da infecção por HIV, em pacientes com diarreia internados nos serviços de medicina interna, HCM (Março de 2016 - Março de 2017)

As Infecções por Cryptosporidium spp e Cystoisospora belli são causas importantes de diarréia em pacientes com VIH (Vírus de Imunodeficiência humana). No entanto, informações relativas a estes dois parasitas são escassas em muitos países africanos, incluindo Moçambique. Objectivos...

Frequencia e caracterização dos genótipos de rotavirus do grupo A em crianças de 0 a 59 meses de idade, atendidas com diarreeia aguda na pediatria do Hospital Central de Nampula, 2015

A doença diarreica na infância constitui um importante problema de saúde pública em Moçambique. A infecção pelo Rotavirus é a uma das causas mais comum de diarreia aguda grave a nível mundial, sendo a diarreia terceira causa de morbi-mortalidade infantil na maioria d...

Association between Precipitation and Diarrheal Disease in Mozambique

Diarrheal diseases are a leading cause of morbidity and mortality in Africa. Although research documents the magnitude and pattern of diarrheal diseases are associated with weather in particular locations, there is limited quantification of this association in sub-Saharan Africa and no studies conducted ...