Nhama, abel;
Nhamússua, lídia;
Macete, eusébio;
Bassat, quique;
Salvador, crizolgo;
Enosse, sónia;
Candrinho, baltazar;
Carvalho, eva;
Nhacolo, arsénio;
Chidimatembue, arlindo;
Saifodine, abuchahama;
Zulliger, rose;
Lucchi, naomi;
Svigel, samaly s;
Moriarty, leah f;
Halsey, eric s;
Mayor, alfredo;
Aide, pedro.
Background: Artemisinin-based combination therapy (ACT) has been the recommended first-line treatment for uncomplicated malaria in Mozambique since 2006, with artemether–lumefantrine (AL) and amodiaquine–artesunate (AS–AQ) as the first choice. To assess efficacy of currently used ACT, an in vivo...
Mozambique/epidemiology,
Artemether/administration & dosage,
Artesunate/administration & dosage,
Algorithms,
Malaria, Falciparum,
Malaria/drug therapy,
Lumefantrine,
Infections,
Efficacy/methods,
34628,
Patients,
Parasites,
Lost to Follow-Up,
Polymerase Chain Reaction,
Recurrence,
Safety,
Therapeutics,
Molecular Diagnostic Techniques
Introdução: Moçambique é um dos países endémicos à malária. Em 2011, a estimativa de prevalência desta doença era de 40–80% em crianças dos 2–9 anos e 90% em crianças menores de 5 anos. Estas altas prevalências podem ser devido à dificuldade das crianças em desenvolverem uma resposta i...
Background: In Mozambique, socio-economic and cultural factors influence the wide adoption of disease preventive measures that are relevant for malaria control strategies to promote early recognition of disease, prompt seeking of medical care, sleeping under insecticide-treated nets (ITNs), and taking i...
Socioeconomic Factors,
Cultural Factors,
Cross-Sectional Studies,
Surveys and Questionnaires,
Malaria/prevention & control,
Mozambique,
Health Knowledge, Attitudes, Practice,
Malaria/psychology,
Rural Population/statistics & numerical data
Galatas, beatriz;
Nhantumbo, hoticha;
Soares, rodolfo;
Djive, helder;
Murato, ilda;
Simone, wilson;
Macete, eusebio;
Rabinovich, n regina;
Alonso, pedro;
Candrinho, baltazar;
Saúte, francisco;
Aide, pedro;
Munguambe, khátia.
Background This study aimed to capture the acceptability prior to, during and after the implementation of the first year of MDA rounds conducted under the Magude project, a malaria elimination project in southern Mozambique. Methods This was amixed-methods study, consisting of focus group discussions (FG...
Anti-Retroviral Agents/analysis,
Mass Drug Administration,
Antimalarials,
Attitude,
Health Strategies,
Residence Characteristics,
Behavior,
Knowledge,
Malaria,
Fear,
Women,
Methods,
Forecasting,
Malaria/drug therapy,
Pharmaceutical Preparations/supply & distribution,
Mozambique
Gupta, himanshu;
Bassat, quique;
Nhamussua, lidia;
Matambisso, gloria;
Cisteró, pau;
Huijben, silvie;
Chidimatembue, arlindo;
Galatas, beatriz;
Ménard, didier;
Ringwald, pascal;
Rabinovich, regina;
Alonso, pedro L;
Saute, francisco;
Assessor, pedro;
Prefeito, alfredo.
Background Mass drug administration (MDA) can rapidly reduce the burden of Plasmodium falciparum (Pf). However, concerns remain about its contribution to select for antimalarial drug resistance. Methods We used Sanger sequencing and real-time PCR to determine the proportion of molecular markers associate...
Antimalarials/administration & dosage,
Antimalarials/pharmacology,
Antimalarials/therapeutic use,
Artemisinins/administration & dosage,
Artemisinins/pharmacology,
Artemisinins/therapeutic use,
Antineoplastic Combined Chemotherapy Protocols,
Drug Resistance/genetics,
Malaria/parasitology,
Malaria/prevention & control,
Mozambique,
Plasmodium falciparum/immunology,
Plasmodium falciparum/genetics,
Plasmodium falciparum/pathogenicity,
Polymorphism, Genetic,
Protozoan Proteins/genetics,
Protozoan Proteins/metabolism,
Quinolines/administration & dosage,
Quinolines/therapeutic use,
Quinolines/pharmacology
Ciera, Leia;
Galatas, Beatriz;
Alonso, Sergi;
Peaijimas, Krijin;
Mamuque, Miler;
Marti-Solar, Helena;
Guinovart, Caterina;
Munguambe, Humberto;
Luis, Fabiao;
Nhantumbo, Hoticha;
Montana, Julia;
Bassat, Quique;
Candrinho, Baltazar.
As new combinations of interventions aiming at interrupting malaria transmission are under evaluation, understanding the associated economic costs and benefits is critical for decision-making. This study assessed the economic cost and cost-effectiveness of the Magude project, a malaria elimination initia...
Abílio, ana paula;
Obi, emmanuel;
Koenker, hannah;
Babalola, stella;
Saifodine, abuchahama;
Zulliger, rose;
Swamidoss, Isabel;
Leon, gabriel ponce de;
Alfai, Eunice;
Blaufuss, sean;
Olapeju, Bolanle;
Harig, hunter;
Kilian, albert.
Malaria prevention with long-lasting insecticidal nets (LLINs) has seen a tremendous scale-up in sub-Saharan Africa in the last decade. To sustain this success, it is important to understand how long LLINs remain in the households and continue to protect net users, which is termed durability. This inform...
Malaria remains one of the most prevalent infectious diseases in the tropics and subtropics, andMozambiqueisnotanexception. To design geographically targeted and effective intervention mechanisms of malaria, an up-to-date map that shows the spatial distribution of malaria is needed. This study analyzed 2...
Malaria/epidemiology,
Residence Characteristics,
Communicable Diseases,
Tropical Ecosystem,
Indicators and Reagents,
Infections/mortality,
Mozambique/epidemiology,
Surveys and Questionnaires/statistics & numerical data,
Mothers/education,
Methods,
Prevalence,
Probability,
Risk,
Public Health,
Mortality/trends
Galatas, beatriz;
Nhacolo, ariel;
Marti, helena;
Munguambe, humberto;
Jamise, edgar;
Guinovart, caterina;
Cirera, laia;
Amone, felimone;
Macete, eusébio;
Bassat, quique;
Rabinovich, regina;
Alonsok, pedro;
Sacoor, charfudin;
Saute, francisco;
Aide, pedro.
Objectives: A Demographic and Health Platform was established in Magude in 2015, prior to the deployment of a project aiming to evaluate the feasibility of malaria elimination in southern Mozambique, named the Magude project. This platform aimed to inform the design, implementation and evaluation of the ...
Cumbane, Victória;
Imbach, Michelle;
Matavele, Raquel;
Macicame, ivalda;
Eller, Leigh;
Lawlor, john;
Milazzo, Mark;
Li, Qun;
Crowell, Trevor;
Mutombene, Mirna;
Guiliche, onelia;
Viegas, edna;
Nwoga, chiaka;
Yates, Adam;
Michael, Nelson;
Robb, Merlin;
Polyak, Christina S;
Jani, ilesh v;
Bhatt, nilesh.
n many African countries, laboratory reference values are not established for the local
healthy adult population. In Mozambique, reference values are known for young adults (18-
24yo) but not yet established for a wider age range. Our study aimed to establish hematological, biochemical and immunological ...
