Resultados: 20

Risk factors for neonatal mortality: an observational cohort study in Sarlahi district of rural southern Nepal

BMJ Open; 13 (9), 2023
Objectives: To assess the association between maternal characteristics, adverse birth outcomes (small-for-gestational-age (SGA) and/or preterm) and neonatal mortality in rural Nepal. Design: This is a secondary observational analysis to identify risk factors for neonatal mortality, using data from a rand...

Study design and rationale for the PAASIM project: a matched cohort study on urban water supply improvements and infant enteric pathogen infection, gut microbiome development and health in Mozambique

BMJ; 3 (13), 2023
Introduction: Despite clear linkages between provision of clean water and improvements in child health, limited information exists about the health impacts of large water infrastructure improvements in low-income settings. Billions of dollars are spent annually to improve urban water supply, and rigorou...

Examining oral pre-exposure prophylaxis (PrEP) literacy among participants in an HIV vaccine trial preparedness cohort study

Background: Internationally-accredited laboratories are recognised for their superior test reliability, operational performance, quality management and competence. In a bid to meet international quality standards, the Mozambique National Institute of Health enrolled the National Tuberculosis Reference La...

Cohort Profile Update: Manhiça Health and Demographic Surveillance System (HDSS) of the Manhiça Health Research Centre (CISM)

Int. j. epidemiol; 17 (4), 2022
The Manhic¸a Health Research Centre [Centro de Investigac¸~ao em Sau´de de Manhic¸a (CISM)] has been running a Health and Demographic Surveillance System (HDSS) since 1996, in the district of Manhic¸a, 80 km North of Maputo City (the capital of Mozambique). As indicated in the original cohort profil...

Retencao e abandono ao tratamento antiretroviral em pacientes dos 10 aos 24 anos de idadeavaliada aos 6, 12 e 18 meses, coorte de 2017. Retencao de pacientes em tratamento antirretroviral em Mocambique

Dados do Programa Conjunto das Nações Unidas para HIV/SIDA (ONUSIDA), estimam que, em 2018, 2.2 milhões de pessoas viviam com HIV (PVHIV). Destas, 56% faziam Tratamento Antirretroviral (TARV) e apenas 45% estavam em supressão viral (< 1000 cópias/mL). Vários são os factores que podem estar associa...

Pregnancy cohorts and biobanking in sub-Saharan Africa: a systematic review

BMJ glob. health; 5 (11), 2020
Background: Technological advances and high throughput biological assays can facilitate discovery science in biobanks from population cohorts, including pregnant women. Biological pathways associated with health outcomes differ depending on geography, and high-income country data may not generalise to lo...

Analise de uma coorte de pacientes que iniciaram o tratamento anirotroviral no ano 2017 - retencao avaliada aos 6, 12 e 18 meses

Em 2018 Moçambique contava com cerca de 2.2 milhões de pessoas vivendo com HIV (PVHIV), e destas 55% (1.212.562) eram pacientes activos em Tratamento Antiretroviral (TARV), segundo as estimativas de modelagem do Programa Conjunto das Nações Unidas para HIV/SIDA (ONUSIDA) de 2019. Um dos maiores desaf...

Loss to follow-up and opportunities for reengagement in HIV care in rural Mozambique. A prospective cohort study

Medicine journal; 99 (6), 2020
Patients lost to follow-up (LTFU) over the human immunodeficiency virus (HIV) cascade have poor clinical outcomes and contribute to onward HIV transmission. We assessed true care outcomes and factors associated with successful reengagement in patients LTFU in southern Mozambique. Newly diagnosed HIV-posi...

The economic burden of malaria on households and the health system in a high transmission district of Mozambique

Malar. j. (Online); 18 (360), 2019
: Malaria remains a leading cause of morbidity and mortality in Mozambique. Increased investments in malaria control have reduced the burden, but few studies have estimated the costs of malaria in the country. This paper estimates the economic costs associated with malaria care to households and to the h...

Protocol and baseline data for a multi-year cohort study of the effects of different mass drug treatment approaches on functional morbidities from schistosomiasis in four African countries

BMC infect. dis; 17 (1), 2017
Background: The Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) focus is on randomized trials of different approaches to mass drug administration (MDA) in endemic countries in Africa. Because their studies provided an opportunity to evaluate the effects of mass treatment on Sch...