With the increase in uptake of multi-month antiretroviral therapy dispensing (MMD) for children, little is known about consistency of MMD receipt over time and its association with virological outcomes. This analysis aims to assess the uptake of 3-month MMD among children, consistent receipt of MMD after...
Background Cost-efectiveness analysis (CEA) is a standard tool for evaluating health programs and informing decisions about resource allocation and prioritization. Most CEAs evaluating health interventions in low- and middle-income countries adopt a health sector perspective, accounting for resources fun...
O Inquérito sobre o Impacto do HIV e SIDA em Moçambique (INSIDA 2021) foi um inquérito nacional baseado nos agregados familiares, conduzido entre Abril de 2021 e Fevereiro de 2022, visando medir o impacto da resposta nacional ao HIV. O INSIDA 2021 ofereceu aconselhamento e testagem de HIV com entrega ...
Background: Sub-Saharan Africa reported 550,000 new HIV infections among women in 2018. Pregnancy and the postpartum period are associated with an increased risk of HIV acquisition (adjusted risk ratio [RR]: 2.8 during pregnancy and 4.0 in postpartum period vs. non-pregnant or postpartum women, respectiv...
Retention in anti-retroviral therapy (ART) presents a challenge in sub-Saharan Africa. In
Mozambique, after roll-out to peripheral facilities, the 12-month retention rate was reported
mostly from sites with an electronic patient tracking system (EPTS), representing only 65%
of patients. We conducted a na...
Fármacos Anti-HIV/farmacologia,
Contagem de Linfócito CD4,
Morte,
Perda de Seguimento,
Sistemas de Identificação de Pacientes,
HIV,
Adolescente,
Moçambique/epidemiologia,
Teste de HIV,
Antirretrovirais/uso terapêutico,
HIV/efeitos dos fármacos,
Gravidez
Castillo, Paola;
Martinez, Miguel J;
Ussene, Esperança;
Jordao, Dercio;
Lovane, Luciliao;
Ismail, Mamudo R;
Carrilho, Carla;
Lorenzoni, Cesaltina;
Fernandes, Fabiola;
Bene, Rosa;
Palhares, Antonio;
Ferreira, Luiz;
Mandomando, Inacio;
Vila, Jordi;
Hurtado, Juan Carlos;
Munguambe, Khátia;
Maixenchs, Maria;
Sanz, Ariadna;
Quinto, Llorenç;
Macete, Eusebio;
Alonso, Pedro;
Bassat, Quique;
Menendez, lara;
Ordi, Jaume.
There is an urgent need to identify tools able to provide reliable information on the cause of death in low-income regions, since current methods (verbal autopsy, clinical records, and complete autopsies) are either inaccurate, not feasible, or poorly accepted. We aimed to compare the performance of a st...
Maixenchs, maria;
Boene, helena;
Anselmo, rui;
Mindu, carolina;
Alonso, pedro;
Menéndez, clara;
Macete, Eusébio;
Pool, robert;
Letang, emílio;
Naniche, denise;
Munguambe, khátia.
Objective: The objective of this qualitative study was to explore how clinical symptoms may affect adherence to antiretroviral therapy (ART) in HIV patients, and to explore factors, perceptions and attitudes related to adherence to therapy.
Design: A qualitative study was carried out in the context of th...
Antirretrovirais/efeitos adversos,
Antirretrovirais/uso terapêutico,
Terapia Antirretroviral de Alta Atividade/efeitos adversos,
Características da Família,
HIV/efeitos dos fármacos,
Infecções por HIV/tratamento farmacológico,
Infecções por HIV/epidemiologia,
Hospitais Rurais,
Adesão à Medicação,
Estudos Prospectivos,
Pesquisa Qualitativa,
Fatores Socioeconômicos,
Moçambique/epidemiologia
This is a substudy of the Agence Nationale de Recherches sur le Sida et les Hépatites Virales (ANRS) Comparison of Nevirapine and Efavirenz for the Treatment of HIV-TB Co-infected Patients (ANRS 12146-CARINEMO) trial, which assessed the pharmacokinetics of rifampin or isoniazid with or without the coadm...
HIV/efeitos dos fármacos,
Antituberculosos/administração & dosagem,
Benzoxazinas,
Mycobacterium,
Mycobacterium tuberculosis/efeitos dos fármacos,
Tuberculose/tratamento farmacológico,
Síndrome da Imunodeficiência Adquirida/epidemiologia,
Soroprevalência de HIV/tendências,
Hepatite/diagnóstico,
Antígenos CD4/efeitos dos fármacos,
Moçambique/epidemiologia
Ao longo de algumas décadas, a epidemia do HIV e SIDA tornou-se num ícone de grandes questões que afligem o mundo devido a sua dinâmica que configura suas manifestações de acordo com as características culturais e sócio demográficas em diferentes populações. O HIV e SIDA constitui um dos grand...
Bergeron, michèle;
Daneau, géraldine;
Ding, tao;
Sitoe, Nádia;
Westerman, larry, e;
Stokx, jocelijn;
Jani, ilesh, v;
Coetzee, lindi, m;
Scott, lesley;
Weggheleire, anja de;
Boel, Luc;
Stevens, wendy, s;
Glencross, deborah;
Peter, trevor, f.
Introduction: Point-of-care (POC) CD4 testing can improve access to treatment by enabling decentralization and reducing patient loss-to-follow-up. As new POC CD4 technologies become available, their performance should be assessed before widespread deployment. This study reports the findings of five indep...
