Introdução: Moçambique implementa a Prevenção da Transmissão Vertical (PTV) do HIV como parte do Programa Nacional desde 2002. Apesar dos ganhos, a taxa de transmissão vertical continua elevada, estimada em 9% em 2023. Descrevemos o progresso da PTV nas Unidades Sanitárias (US) apoidas pelo PEPFA...
Introdução: A Circuncisão Masculina Médica Voluntária (CMMV) é uma estratégia de prevenção do HIV com boa relação custo-eficácia, reduzindo o risco de transmissão de mulher para homem em aproximadamente 60%. Moçambique implementa o programa nacional de CMMV desde 2010, incluindo testagem de...
O sistema de saúde em Moçambique está em constante adaptação para fazer frente às doenças infecciosas endémicas, doenças infecciosas emergentes, doenças não transmissíveis e trauma,
especialmente tendo em conta a evolução das dinâmicas socio-económicas e ambientais. Embora
o fardo relat...
Mozambique has one of the world's highest HIV/AIDS burdens. Despite significant investment in HIV care and treatment, pregnant and lactating women's retention in care remains suboptimal. One reason for poor maternal retention is lack of male partner support. We tested an interventional couple-based HIV c...
Vubil, Adolfo;
Zicai, Ana Flora;
Sitoe, Nádia;
Nhachigule, Carina;
Costa, Paulino da;
Magul, Cacildo;
Meggi, Bindiya;
Viegas, Sofia;
Mabunda, Nédio;
Jani, Ilesh.
ABSTRACT Dried blood spot (DBS) may overestimate the viral RNA, mainly in patients
with low viral load (VL), due to proviral DNA and intracellular RNA. The Burnett and
HemaSpot provide integrated solutions for the collection, separation, and drying of
plasma from whole blood. This study aims to evalua...
Chabala, Chishala;
Jacobs, Tom G;
Moraleda, Cinta;
Ndaferankhande, John M;
Mumbiro, Vivian;
Passanduca, Alfeu;
Namuziya, Natasha;
Nalwanga, Damalie;
Musiime, Victor;
Ballesteros, Alvaro;
Domínguez-Rodríguez, Sara;
Chitsamatanga, Moses;
Cassia, Uneisse;
Nduna, Bwendo;
Bramugy, Justina;
Sacarlal, Jahit;
Madrid, Lola;
Nathoo, Kusum J;
Colbers, Angela;
Burger, David M;
Mulenga, Veronica;
Buck, W Chris;
Mujuru, Hilda A;
Te Brake, Lindsey H M;
Rojo, Pablo;
Tagarro, Alfredo;
Aarnoutse, Rob E.
Optimal antituberculosis therapy is essential for favorable
clinical outcomes. Peak plasma concentrations of first-line
antituberculosis drugs in infants with living HIV receiving
WHO-recommended dosing were low compared with reference values for adults, supporting studies on increased doses of
first-lin...
Benoni, Roberto;
Casigliani, Virginia;
Zin, Annachiara;
Ronzoni, Niccolò;
Di Chiara, Costanza;
Merolle, Ada;
Guambe Dos Anjos, Helga;
Chenene, Fernando;
Tognon, Francesca;
Putoto, Giovanni;
Giaquinto, Carlo.
n In Sofala province (Mozambique), young people living with HIV (YPLHIV) are estimated at 7%
among people aged 15–24 years. Even though the COVID-19 pandemic threatened HIV health services, data
on the impact of COVID-19 on YPLHIV people are lacking. This study aimed at exploring the seroprevalence o...
Olbrich, laura;
Verghese, Valsan, P;
Smith, zoe franckling;
Sabi, issa;
Ntinginya, Nyanda E;
Mfinanga, alfred;
Banze, denise;
Viegas, sofia omar;
Khosa, celso;
Semphere, robina.
Background Childhood tuberculosis remains a major cause of morbidity and mortality in part due to missed diagnosis. Diagnostic methods with enhanced sensitivity using easy-to-obtain specimens are needed. We aimed to assess the diagnostic accuracy of the Cepheid Mycobacterium tuberculosis Host Response pr...
Approximately 15% of people with HIV in sub-Saharan Africa have comorbid depression, which impacts treatment outcomes. We describe predictors of baseline depressive symptoms in 1079 female and 1079 male participants in a cluster-randomized trial in Zambézia Province, Mozambique from November 2017 to Dec...
Schacht, caroline de;
Amorim, gustavo;
Rompaey, sara van;
Melo, mayra;
Verissimo, cheinaze;
Naftal, anibal;
Graves, erin;
Bilhete, fernandes;
Tique, josé;
Wester, c william.
The community adherence support group (CASG) was one of the first differentiated service delivery (DSD) models introduced in Mozambique. This study assessed the impact of this model on retention in care, loss to follow-up (LTFU), and viral suppression among antiretroviral therapy (ART)-treated adults in ...
