Objectives: A Demographic and Health Platform was established in Magude in 2015, prior to the deployment of a project aiming to evaluate the feasibility of malaria elimination in southern Mozambique, named the Magude project. This platform aimed to inform the design, implementation and evaluation of the ...
Background: Conceptualizing gender dynamics and ways of bridging entrenched gender roles will contribute to better health promotion, policy and planning. Such processes are explored in relation to malaria in Mozambique. Methods: A multi-method, qualitative study using focus group discussions (FGDs) and i...
Community health workers (CHWs) provide preventive care and integrated community case management (iCCM) to people with low healthcare access worldwide. CHW programmes have helped reduce mortality in
myriad countries, but little data on malaria supply chain management has been shared. This project evaluat...
A diversidade genética do Plasmodium falciparum é um dos maiores obstáculos para o desenvolvimento da imunidade assim como para a eficácia terapêutica de antimaláricos, pois confere ao parasita habilidade para evadir a resposta imune do hospedeiro, gerando mudanças na sua composição antigénica,...
Given the high morbidity for mother and fetus associated with malaria in pregnancy, safe and efficacious drugs are needed for treatment. Artemisinin derivatives are the most effective antimalarials, but are associated with teratogenic and embryotoxic effects in animal models when used in early pregnancy....
Background: Dihydroartemisinin-piperaquine (DHA-PQ) is one of five WHO recommended artemisinin combination therapy (ACT) for the treatment of uncomplicated malaria. However, little was known on its post-registration safety and effectiveness in sub-Saharan Africa. DHA-PQ provides a long post-treatment pro...
A malária e HIV/SIDA representam os dois principais problemas de saúde pública no mundo. O efeito da imunodepressão causada pelo HIV/SIDA afecta a resposta imune do hospedeiro contra a malária; contudo estudos sobre o impactodo HIV/SIDA na resposta humoral contra Pl...
Background. Intermittent preventive treatment in infants (IPTi) with sulfadoxine-pyrimethamine (SP) is a po tential malaria control strategy. There is concern about the impact that increasing in vivo resistance to SP has on the efficacy of IPTi, as well as about the potential contribution of IPTi to incr...
