Resultados: 18

Demographic and health community-based surveys to inform a malaria elimination project in magude district, southern Mozambique

BMJ Open; 10 (5), 2020
Objectives: A Demographic and Health Platform was established in Magude in 2015, prior to the deployment of a project aiming to evaluate the feasibility of malaria elimination in southern Mozambique, named the Magude project. This platform aimed to inform the design, implementation and evaluation of the ...

“We have this, with my husband, we live in harmony”: exploring the gendered decision-making matrix for malaria prevention and treatment in Nampula Province, Mozambique

Malar. j. (Online); 19 (133), 2020
Background: Conceptualizing gender dynamics and ways of bridging entrenched gender roles will contribute to better health promotion, policy and planning. Such processes are explored in relation to malaria in Mozambique. Methods: A multi-method, qualitative study using focus group discussions (FGDs) and i...

Malaria case management commodity supply and use by community health workers in Mozambique, 2017

Malar. j. (Online); 18 (47), 2019
Community health workers (CHWs) provide preventive care and integrated community case management (iCCM) to people with low healthcare access worldwide. CHW programmes have helped reduce mortality in myriad countries, but little data on malaria supply chain management has been shared. This project evaluat...

Diversidade genética de plasmodium falciparsum em amostras de crianças menores de 5 anos de dois distritos de Moçambique
genetic diversity of plasmodium falciparsum in samples from children under 5 from two districts in Mozambique

A diversidade genética do Plasmodium falciparum é um dos maiores obstáculos para o desenvolvimento da imunidade assim como para a eficácia terapêutica de antimaláricos, pois confere ao parasita habilidade para evadir a resposta imune do hospedeiro, gerando mudanças na sua composição antigénica,...

The Safety of Artemisinin Derivatives for the Treatment of Malaria in the 2nd or 3rd Trimester of Pregnancy: A Systematic Review and Meta-Analysis

PLos ONE; 11 (11), 2016
Given the high morbidity for mother and fetus associated with malaria in pregnancy, safe and efficacious drugs are needed for treatment. Artemisinin derivatives are the most effective antimalarials, but are associated with teratogenic and embryotoxic effects in animal models when used in early pregnancy....

Treatment outcomes in a safety observational study of dihydroartemisinin/piperaquine (Eurartesim(®)) in the treatment of uncomplicated malaria at public health facilities in four African countries

Malar. j. (Online); 15 (43), 2016
Background: Dihydroartemisinin-piperaquine (DHA-PQ) is one of five WHO recommended artemisinin combination therapy (ACT) for the treatment of uncomplicated malaria. However, little was known on its post-registration safety and effectiveness in sub-Saharan Africa. DHA-PQ provides a long post-treatment pro...

Resposta humoral contra antígenos do plasmodium falciparum em pacientes com malária e co-infectados pelo HIV

A malária e HIV/SIDA representam os dois principais problemas de saúde pública no mundo. O efeito da imunodepressão causada pelo HIV/SIDA afecta a resposta imune do hospedeiro contra a malária; contudo estudos sobre o impactodo HIV/SIDA na resposta humoral contra Pl...

Molecular Markers of Resistance to Sulfadoxine-Pyrimethamine during Intermittent Preventive Treatment for Malaria in Mozambican Infants

J. infect. dis; 197 (12), 2008
Background. Intermittent preventive treatment in infants (IPTi) with sulfadoxine-pyrimethamine (SP) is a po tential malaria control strategy. There is concern about the impact that increasing in vivo resistance to SP has on the efficacy of IPTi, as well as about the potential contribution of IPTi to incr...