Resultados: 227

Prevalence, incidence and determinants of herpes simplex virus type 2 infection among HIV-seronegative women at high-risk of HIV infection: a prospective study in Beira, Mozambique

PLos ONE; 9 (2), 2014
To estimate the prevalence, incidence and determinants of herpes simplex type 2 (HSV-2) infection, and associations between HSV-2 and incident HIV infection, among women at higher risk for HIV infection in Beira, Mozambique. Methods: Between 2009 and 2012, 411 women aged 18-35 years at higher risk of HI...

HIV incidence in a cohort of women at higher risk in Beira, Mozambique: prospective study 2009-2012

PLos ONE; 9 (1), 2014
Background: HIV is prevalent in Sofala Province, Mozambique. To inform future prevention research, we undertook a study in the provincial capital (Beira) to measure HIV incidence in women at higher risk of HIV and assess the feasibility of recruiting and retaining them as research participants. Methods:...

Willingness to participate in future HIV prevention trials in Beira, Mozambique

In preparation for trials of new HIV prevention methods; willingness to participate (WTP) was assessed in Beira; Mozambique. A totla of 1 019 women participating in an HIV incidence study; and 97 men participating in a separate WTP survey; were interviewed. When comparing the answers to questions that we...

Genetic Analysis and Natural Polymorphisms in HIV-1 gp41 Isolates from Maputo City, Mozambique

AIDS res. hum. retrovir; 30 (6), 2013
Enfuvirtide was the first fusion inhibitor approved by the Food and Drug Administration (FDA) in 2003 for HIV-1 infection in treatment-experienced patient. It is the first approved antiviral agent to attack the HIV life cycle in its early stages. For HIV fusion to occur, the HR1 and HR2 domains in the gp...

Breast milk and gut microbiota in African mothers and infants from an area of high HIV prevalence

PLos ONE; 8 (11), 2013
Human milk and infant gut microbiota are essential for the immune system maturation and protection against infections. There is scarce information on the microbiological composition of breast milk in general, and none from developing countries. The objective of the study was to characterize the breast mi...

Educational Intervention Increased Referrals to Allopathic Care by Traditional Healers in Three High HIV-Prevalence Rural Districts in Mozambique

PLos ONE; 8 (8), 2013
Introduction: Delayed uptake of clinical services impedes favorable clinical outcomes in Mozambique. Care is delayed among patients who initiate care with traditional healers; patients with conditions like human immunodeficiency virus (HIV) or tuberculosis are rarely referred to the health system in a ti...

Evolution of primary HIV drug resistance in a subtype C dominated epidemic in Mozambique
Evolution of primary HIV drug resistance in a subtype C dominated epidemic in Mozambique

PLos ONE; 8 (7), 2013
Em Moçambique, o tratamento anti-retroviral altamente activo (HAART) foi introduzido em 2004, seguido de descentralização e expansão, resultando num aumento de mais de 20 vezes na cobertura até 2009. A implementação de inquéritos sobre limiares de resistência aos medicamentos contra o VIH (HIVDR...

Routine data from prevention of mother-to-child transmission (PMTCT) HIV testing not yet ready for HIV surveillance in Mozambique: a retrospective analysis of matched test results

BMC infect. dis; 13 (244), 2013
Mozambique through the prevention of mother-to-child transmission (PMTCT) program. If routine data from this program were of sufficient quality, their heightened coverage and continuous availability could complement or even replace biannual sentinel serosurveys that currently serve as the primary HIV sur...

Determinants of prevalent HIV infection and late HIV diagnosis among young women with two or more sexual partners in Beira, Mozambique

PLos ONE; 8 (5), 2013
Background: The prevalence and determinants of HIV and late diagnosis of HIV in young women in Beira, Mozambique, were estimated in preparation for HIV prevention trials. Methods: An HIV prevalence survey was conducted between December 2009 and October 2012 among 1,018 women aged 18-35 with two or more ...

Avaliação do potencial papel do toxoplasma gondiina encefalite relacionada com infecção pelo HIV em doentes internados no hospital central de Maputo

Toxoplasmose é uma doença parasitária causada por Toxoplasma gondii (T. gondii). O T. gondii, em pacientes imunocompetentes, geralmente causa infecções assintomáticas e latentes. Em doentes imunocomprometidos, a reactivação de toxoplasmose latente no Sistema Nervoso Central (SNC), pode causar doe...