Resultados: 284

Perfil imunológico, virológico e expressão de CD38 pelas células TCD8; dos pacientes monoinfectados HIV-1 positivos e coinfectados HIV/TB seguidos no centro de saúde da polana caniço

Segundo OMS, em 2013 aproximadamente 35 milhões de pessoas no Mundo estavam infectadas pelo HIV e destes, aproximadamente 24,7 milhões viviam na África Subsariana. Em Moçambique, a prevalência é de 11,5% na população com 15-49 anos de idade. O aumento da prevalência do HIV na década de 80, prov...

Radiological findings in young children investigated for tuberculosis in Mozambique

PLos ONE; 10 (5), 2015
Introduction: Chest radiography remains a critical tool for diagnosing intrathoracic tuberculosis (TB) in young children who are unable to expectorate. We describe the radiological findings in children under 3 years of age investigated for TB in the district of Manhiça, southern Mozambique, an area with...

Molecular characterization of mycobacterium tuberculosis complex isolates in mozambique

Mozambique is one of the high burden tuberculosis (TB) and human immunodeficiency virus (HIV) countries with a prevalence of HIV infection in adults of 11.5% and an estimated TB prevalence of 559 per 100 000 population. Fifty six percent of the TB patients in Mozambique are estimated to be HIV positive. ...

CD4+CD25High Treg cells in HIV/HTLV Co-infected patients with neuropathy: high expression of Alpha4 integrin and lower expression of Foxp3 transcription factor
CD4(+)CD25(High) Treg cells in HIV/HTLV co-infected patients with neuropathy: high expression of Alpha4 integrin and lower expression of Foxp3 transcription factor

BMC immunol. (Online); 16 (52), 2015
As células T CD4 reguladoras (Tregs) são críticas na manutenção da homeostase do sistema imunológico. Alterações quantitativas ou fenotípicas e comprometimento funcional de Tregs têm sido associados ao desenvolvimento de patologias incluindo as do sistema nervoso central. Indivíduos com coinfe...

Adolescentes e jovens em moçambique: uma perspectiva demografica em saude

De acordo com o Censo de 2007, os adolescentes e jovens (10 aos 24 anos) correspondiam a 32% do total da população em Moçambique (INE, 2013). O tamanho deste grupo torna relevante o conhecimento das suas dinâmicas demográfcas e do seu estado de saúde, não só para compreender os determinantes da s...

Access to HIV prevention and care for HIV-exposed and HIV-infected children: a qualitative study in rural and urban Mozambique

BMC public health (Online); 14 (1240), 2014
Background: Follow-up of HIV-exposed children for the delivery of prevention of mother-to-child transmission services and for early diagnosis and treatment of HIV infection is critical to their survival. Despite efforts, uptake of postnatal care for these children remains low in many sub-Saharan African ...

HIV prevalence and risk behaviors among Mozambicans working in South African mines

AIDS behav; 19 (1), 2014
Mineworkers are considered a population at risk for HIV due to risk behaviors associated with migratory work patterns. This was the first study in Mozambique to determine the prevalence of HIV and associated demographic and risk behaviors, and assess use and access to prevention and healthcare services a...

A combination strategy for enhancing linkage to and retention in HIV care among adults newly diagnosed with HIV in Mozambique: study protocol for a site-randomized implementation science study

BMC infect. dis; 14 (549), 2014
Background: Despite the extraordinary scale up of HIV prevention, care and treatment services in sub-Saharan Africa (SSA) over the past decade, the overall effectiveness of HIV programs has been significantly hindered by high levels of attrition across the HIV care continuum. Data from “real-life” se...

Evaluation of performance and acceptability of two rapid oral fluid tests for HIV detection in Mozambique

J. clin. microbiol; 52 (10), 2014
Simplified HIV testing based on oral fluid (OF) may allow the expansion of HIV infection counseling and testing (CT) while reducing the risk due to exposure to needles and blood collection. This study evaluated the performance and acceptability of two OF tests (the OraQuick Advance Rapid HIV-1/2 and the ...

Intermittent preventive treatment of malaria in pregnancy with mefloquine in HIV-negative women: a multicentre randomized controlled trial

PloS med; 11 (9), 2014
Background: Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommended by WHO to prevent malaria in African pregnant women. The spread of SP parasite resistance has raised concerns regarding long-term use for IPT. Mefloquine (MQ) is the most promising of avai...