As infecções pelo Plasmodium falciparum (P.falciparum) e pelo Vírus da Imunodeficiência Humana (HIV) constituem problema de Saúde Pública particularmente na África subsaariana onde as duas infecções têm o seu maior peso. A sobreposição geográfica das duas infecções implica a ocorrência da...
Plasmodium falciparum,
Infecções por HIV,
Malária/complicações,
Malária/diagnóstico,
Pacientes,
T-Linfocitopenia Idiopática CD4-Positiva,
Variação Genética,
Merozoítos,
Moçambique,
Antimaláricos/imunologia,
Antígenos CD4
HIV proviral DNA integration into the host chromosome is carried out by integrase becoming an important arget antiretroviral therapy. Raltegravir was the first integrase inhibitor approved for use in HIV therapy andelvitegravir is in the late phase of clinical development; both show good results in monot...
DNA Viral/química,
DNA Viral/genética,
Farmacorresistência Viral,
Variação Genética,
Infecções por HIV/virologia,
Integrase de HIV/genética,
Inibidores de Integrase de HIV/uso terapêutico,
Dados de Sequência Molecular,
Provírus/genética,
Mutação de Sentido Incorreto,
Moçambique/epidemiologia,
Análise de Sequência de DNA/instrumentação
The scale-up of effective HIV viral load (VL) testing is an urgent public health priority. Implementation of testing
is supported by the availability of accurate, nucleic acid based laboratory and point-of-care (POC) VL technologies and strong
WHO guidance recommending routine testing to identify treatme...
The expansion of HIV antiretroviral therapy into decentralized rural settings will increasingly require simple point-of-care (POC) diagnostic tests that can be used without laboratory infrastructure and technical skills. New POC test devices are becoming available but decisions around which technologies ...
Background: The prevalence of hepatitis B virus (HBV) infection and human immunodeficiency virus (HIV) infection in Mozambique is one of the highest in the world, though in spite of this the prevalence of occult hepatitis B infection (OBI) is unknown.
Objectives: This study was conducted with the aim to ...
Chambal, Lúcia Mabalane;
Gudo, Eduardo Samo;
Carimo, Awa;
Real, Rita Corte;
Mabunda, Nédio;
Maueia, Cremildo;
Vubil, Adolfo;
Zicai, Ana Flora;
Bhatt, Nilesh;
Antunes, Francisco.
Background HIV/ HBVcoinfected patients are at high risk of developing chronic HBV infection, liver cir rhosis and hepatocellular carcinoma. In Mozambique, where HIV prevalence is one of the highest in the world, HIV-infected patients are scarcely characterized in terms of HBV coin fection and 3TC-resista...
Bergeron, michèle;
Daneau, géraldine;
Ding, tao;
Sitoe, Nádia;
Westerman, larry, e;
Stokx, jocelijn;
Jani, ilesh, v;
Coetzee, lindi, m;
Scott, lesley;
Weggheleire, anja de;
Boel, Luc;
Stevens, wendy, s;
Glencross, deborah;
Peter, trevor, f.
Introduction: Point-of-care (POC) CD4 testing can improve access to treatment by enabling decentralization and reducing patient loss-to-follow-up. As new POC CD4 technologies become available, their performance should be assessed before widespread deployment. This study reports the findings of five indep...
Saracino, Annalisa;
Nacarapa, Edy A;
da Costa Massinga, Ézio A;
Martinelli, Domenico;
Martinelli, Domenico;
Scacchetti, Marco;
de Oliveira, Carlos;
Antonich, Anita;
Galloni, Donata;
Ferro, Josefo J;
Macome, César A.
Mozambique presents a very high prevalence of both malaria and HIV infection, but the impact of co-cancel infection on morbidity in this population has been rarely investigated. The aim of this study was to describe the prevalence and clinical characteristics of malaria in hospitalized adult HIV-positive...
Objectives: To compare HIV care quality provided by non-physician clinicians (NPC) and physicians.
Design: Retrospective cohort study assessing the relationship between provider cadre and HIV care quality among non-pregnant adult patients initiating antiretroviral therapy (ART) in the national HIV care ...
Schito, Marco;
Peter, Trevor F;
Cavanaugh, Sean;
Piatek, Amy S;
Young, Gloria J;
Alexander, Heather;
Coggin, William;
Domingo, Gonzalo J;
Ellenberger, Dennis;
Ermantraut, Eugen;
Jani, Ilesh V;
Katamba, Achilles;
Palamountain, Kara M;
Essajee, Shaffiq;
Dowdy, David W.
Stakeholders agree that supporting high-quality diagnostics is essential if we are to continue to make strides in the fight against human immunodeficiency virus (HIV) and tuberculosis. Despite the need to strengthen existing laboratory infrastructure, which includes expanding and developing new laborator...
