Total: 1720

Diagnostic accuracy of a three-gene Mycobacterium tuberculosis host response cartridge using fingerstick blood for childhood tuberculosis: a multicentre prospective study in low-income and middle-income countries

Lancet, Infect. dis.; 12 (23), 2023
Background Childhood tuberculosis remains a major cause of morbidity and mortality in part due to missed diagnosis. Diagnostic methods with enhanced sensitivity using easy-to-obtain specimens are needed. We aimed to assess the diagnostic accuracy of the Cepheid Mycobacterium tuberculosis Host Response pr...

Correlated depressive symptoms within seroconcordant, expectant partners living with HIV in Zambézia Province, Mozambique: a cross-sectional study

AIDS care; 35 (11), 2023
Approximately 15% of people with HIV in sub-Saharan Africa have comorbid depression, which impacts treatment outcomes. We describe predictors of baseline depressive symptoms in 1079 female and 1079 male participants in a cluster-randomized trial in Zambézia Province, Mozambique from November 2017 to Dec...

Changing patterns in the burden of paediatric injuries during the COVID-19 pandemic: a study in Mozambique’s central hospitals

Introduction: There is a substantial body of knowledge on the effects of the COVID-19 pandemic on injuries showing frequent but inconsistent reductions in both volume and pattern. Yet, studies specifically addressing children are less common, not least from low- and middle-income countries. This study in...

Association between antenatal care facility readiness and provision of care at the client level and facility level in five low- and middle-income countries

Background: Despite growing interest in monitoring improvements in quality of care, data on service quality in low-income and middle-income countries (LMICs) is limited. While health systems researchers have hypothesized the relationship between facility readiness and provision of care, there have been f...

Efficacy and safety of pyronaridine-artesunate (PYRAMAX) for the treatment of P. falciparum uncomplicated malaria in African pregnant women (PYRAPREG): study protocol for a phase 3, non-inferiority, randomised open-label clinical trial

BMJ Open; 13 (10), 2023
Malaria infection during pregnancy increases the risk of low birth weight and infant mortality and should be prevented and treated. Artemisinin-based combination treatments are generally well tolerated, safe and effective; the most used being artemether-lumefantrine (AL) and dihydroartemisinin-piperaquin...

Favorable Impact of Community Adherence Support Groups on Retention in Care and Viral Suppression Rates Among Persons with HIV Receiving Antiretroviral Therapy in Mozambique

AIDS res. hum. retrovir; 39 (10), 2023
The community adherence support group (CASG) was one of the first differentiated service delivery (DSD) models introduced in Mozambique. This study assessed the impact of this model on retention in care, loss to follow-up (LTFU), and viral suppression among antiretroviral therapy (ART)-treated adults in ...

Arbovirus researchers unite: expanding genomic surveillance for an urgent global need

Lancet Glob. Health; 11 (10), 2023
Arthropod-borne viruses (arboviruses) are transmitted by arthropod vectors to humans, leading to disease outbreaks mainly in tropical regions of the world.1 Although many arboviruses are known, three Aedes-spp-borne viruses are particularly concerning for humans at a global scale due to recurring large a...

Examining comorbidities in children with diarrhea across four provinces of Mozambique: A cross-sectional study (2015 to 2019)

PLos ONE; 14(1) (), 2023
Comorbidities are defined as the simultaneous occurrence of two or more diseases within the same individual. Comorbidities can delay a patient's recovery and increase the costs of treatment. Assessing comorbidities can provide local health care policy-makers with evidence of the most common multi-health ...

The Infomóvel-An information system for managing HIV/AIDS patients in rural areas of Mozambique

Mobile health is gradually revolutionizing the way medical care is delivered worldwide. In Mozambique, a country with a high human immunodeficiency virus prevalence, where antiretroviral treatment coverage is 77% accompanied by a 67% of retention rate, the use of mobile health technology may boost the an...

Perfil clinico-epidemiológico e factores associados à não supressão viral em pacientes vivendo com hiv/sida assistidos no centro integrado de tratamento no hospital militar de maputo (citra/hmm), 2019 à 2020
Clinical-epidemiological profile and factors associated with viral non-suppression in patients living with hiv/aids assisted at the integrated treatment center at the maputo military hospital (citra/hmm), 2019 to 2020

: Introdução: O HIV e SIDA é um problema de saúde pública global, responsável por cerca de 32.7 milhões de mortes de doenças relacionadas à SIDA desde o início da epidemia até o final de 2019, comprometendo a saúde, a força de produção e produtividade. Esse cenário tende a ser mais grave,...