Total: 1827

Differential expression of var subgroups and PfSir2a genes in afebrile Plasmodium falciparum malaria: a matched case-control study

Malar. j. (Online); 18 (1), 2019
Background: Poor knowledge on the afebrile Plasmodium falciparum biology limits elimination approaches to target asymptomatic malaria. Therefore, the association of parasite factors involved in cytoadhesion, parasite multiplication and gametocyte maturation with afebrile malaria was assessed. Methods: Pl...

Mozambique’s Community Antiretroviral Therapy Support Group Program: The Role of Social Relationships in Facilitating HIV/ AIDS Treatment Retention

AIDS behav; 23 (9), 2019
The Community Antiretroviral (ARV) Therapy Support Group (CASG) program aims to address low retention rates in Mozambique’s HIV treatment program and the absorptive capacity of the country’s health facilities. CASG provides patients with the opportunity to form groups, whose members provide peer supp...

Geographic access to emergency obstetric services: a model incorporating patient bypassing using data from Mozambique
Geographic access to emergency obstetric services: a model incorporating patient bypassing using data from Mozambique

BMJ Glob Health; 4 (5), 2019
Targeted approaches to further reduce maternal mortality require thorough understanding of the geographic barriers that women face when seeking care. Common measures of geographic access do not account for the time needed to reach services, despite substantial evidence that links proximity with greater ...

How accurate are modelled birth and pregnancy estimates? Comparison of four models using high resolution maternal health census data in southern Mozambique

BMJ Glob Health; 4 (5), 2019
Background: Existence of inequalities in quality and access to healthcare services at subnational levels has been identified despite a decline in maternal and perinatal mortality rates at national levels, leading to the need to investigate such conditions using geographical analysis. The need to assess t...

A Balanced Proinflammatory and Regulatory Cytokine Signature in Young African Children Is Associated With Lower Risk of Clinical Malaria

Clin. infect. dis; 69 (Sep.2019), 2019
The effect of timing of exposure to first Plasmodium falciparum infections during early childhood on the induction of innate and adaptive cytokine responses and their contribution to the development of clinical malaria immunity is not well established. As part of a double-blind, randomized, placebo-contr...

Tipping the balance towards long-term retention in the HIV care cascade: A mixed methods study in southern Mozambique

PLoS One; 14 (9), 2019
Background: The implementation of quality HIV control programs is crucial for the achievement of the UNAIDS 90-90-90 targets and to motivate people living with HIV (PLWHIV) to link and remain in HIV-care. The aim of this mixed method cross-sectional study was to estimate the linkage and long-term retenti...

Avaliação de necessidades de sistemas de informação em radiologia, nos serviços de radiologia dos hospitais públicos de Moçambique
Needs assessment of information systems in information systems, in the radiology services of public hospitals in Mozambique

A prestação de serviços, como componente essencial do sistema de saúde, refere-se à forma como os recursos são organizados e geridos para assegurar o acesso, a qualidade, a segurança e a continuidade dos cuidados de acordo com as condições de saúde, em diferentes locais e ao longo do tempo. Na ...

Clinico-pathological discrepancies in the diagnosis of causes of death in adults in Mozambique: A retrospective observational study

PLoS One; 14 (9), 2019
Background Clinico-pathological discrepancies are more frequent in settings in which limited diagnostic techniques are available, but there is little information on their actual impact. Aim We assessed the accuracy of the clinical diagnoses in a tertiary referral hospital in sub-Saharan Africa by compari...

Efficacy and safety of dihydroartemisinin-piperaquine for treatment of Plasmodium falciparum uncomplicated malaria in adult patients on antiretroviral therapy in Malawi and Mozambique: an open label non-randomized interventional trial

Malar. j. (Online); 18 (1), 2019
Background: HIV-infected individuals on antiretroviral therapy (ART) require treatment with artemisinin-based combination therapy (ACT) when infected with malaria. Dihydroartemisinin–piperaquine (DPQ) is recommended for treatment of Plasmodium falciparum malaria, but its efcacy and safety has not been ...