Rotavirus (RV) is an important enteric pathogen in the young of many mammalian and avian species. The virus belongs to the Reoviridae family and contains an 11-segmented double-stranded RNA (dsRNA) genome. The dsRNA segments encode six structural (VP1–4, 6 and 7) and six non-structural (NSP1–5/6) pro...
Mozambique introduced rotavirus vaccine (Rotarix, GSK Biologicals) in the National Immunization Program in September 2015 with the objective of reducing the burden of total diarrheal disease and specifically severe rotavirus disease. This study aimed to evaluate the early impact of rotavirus vaccine in r...
Abstract
Background: Diarrheal disease remains a leading cause of illness and death, particularly in low-income countries. Its burden, microbiological causes and risk factors were examined in children aged 0-59 months living in Manhiça, rural southern Mozambique.
Methods: Trends of diarrhea-related burd...