Resultados: 3

Putative pathogen-selected polymorphisms in the PKLR gene are associated with mycobacterial susceptibility in Brazilian and African populations

PLoS Negl Trop Dis; 15 (8), 2021
Investigation of human genes under pathogen-driven selection as Plasmodium sp. has pinpointed genetic variants that participate in the adaptation to the environment and/or are related to severities of human diseases. The current study examined an example of an evolutionary trade-off in which genetic vari...

Natural selection for the Duffy-null allele in the recently admixed people of Madagascar

While gene flow between distantly related populations is increasingly recognized as a potentially important source of adaptive genetic variation for humans, fully characterized examples are rare. In addition, the role that natural selection for resistance to vivax malaria may have played in the extreme d...

Estudo de polimorfismo de genes PKLR e VDR na população de Moçambique
polymorphism study FOR VDR gene and the population of Mozambique

As doenças infecciosas constituem um dos principais problemas de saúde no continente Africano, especialmente na África Subsariana, da qual Moçambique faz parte. A participação de fatores genéticos na susceptibilidade dos humanos às doenças infecciosas é um fato. A identificação de marcadores ...