RDSM – Rede de Documentação sobre Saúde em Moçambique

Rotavirus disease burden pre-vaccine introduction in young children in Rural Southern Mozambique, an area of high HIV prevalence

Acácio, Sozinho; Nhampossa, Tacilta; Quintò, Llorenç; Quintò, Llorenç; Vubil, Delfino; Garrine, Marcelino; Bassat , Quique; Farag, Tamer; Panchalingam, Sandra; Nataro, James P; Kotloff , Karen L; Levine, Myron M; Tennant, Sharon M; Alonso, Pedro L; Mandomando, Inácio.

PLoS One; 16 (4), 2021

Rotavirus vaccines have been adopted in African countries since 2009, including Mozambique (2015). Disease burden data are needed to evaluate the impact of rotavirus vaccine. We report the burden of rotavirus-associated diarrhea in Mozambique from the Global Enteric Multicenter Study (GEMS) before vaccin...

Modelos Logísticos, Moçambique, d0172810, d0123070, Rotavirus/imunologia, Infecções por Rotavirus/epidemiologia, Infecções por Rotavirus/imunologia, Vacinas contra Rotavirus/imunologia

Texto completo

Whole genome analyses of DS-1-like Rotavirus A strains detected in children with acute diarrhoea in southern Mozambique suggest several reassortment events

Rotavirus (RV) is an important enteric pathogen in the young of many mammalian and avian species. The virus belongs to the Reoviridae family and contains an 11-segmented double-stranded RNA (dsRNA) genome. The dsRNA segments encode six structural (VP1–4, 6 and 7) and six non-structural (NSP1–5/6) pro...