Guimarães, Esperança Lourenço;
Chissaque, Assecênio;
Pecenka, Clint;
Clark, Andrew;
Vaz, Basília;
Banze, Arlindo;
Canana, Neide;
Romão, Clésio;
Martins, Maria do Rosário Oliveira;
de Deus, Nilza;
Debellut, Frédéric.
Introduction: Rotavirus is one of the most common cause of severe gastroenteritis in children, with the largest mortality burden in low- and middle-income countries. To prevent rotavirus gastroenteritis, Mozambique introduced ROTARIX vaccine in 2015, however, its cost-effectiveness has never been establi...
Diarreia/tratamento farmacológico,
Rotavirus/imunologia,
Vacinação/efeitos adversos,
Vacinas contra Rotavirus/provisão & distribuição,
Análise de Custo-Efetividade/economia,
Moçambique/epidemiologia,
Diarreia/diagnóstico,
Vacinas contra Rotavirus/imunologia,
Custos de Cuidados de Saúde/normas,
Custos e Análise de Custo/economia,
Análise de Custo-Efetividade/organização & administração
Mozambique introduced monovalent rotavirus vaccine (Rotarix®) in September 2015. We
evaluated the effectiveness of Rotarix® under conditions of routine use in Mozambican children hospitalized with acute gastroenteritis (AGE). A test negative case-control analysis was performed on data collected during ...
Strydom, Amy;
Donato, celeste m;
Nyaga, martin m;
Boene, simone s;
Peenze, Ina;
Mogotsi, Milton T;
João, Eva D;
Munlela, benilde;
Potgieter, A. Christiaan;
Seheri, mapaseka L;
de Deus, Nilsa;
O’Neill, hester G.
This study presents whole genomes of seven bovine rotavirus strains from South Africa and Mozambique. Double-stranded RNA, extracted from stool samples without prior adaptation to cell culture, was used to synthesise cDNA using a self-annealing anchor primer ligated to dsRNA and random hexamers. The cDNA...
Anapakala, Elda;
Chilaúle, Jorfélia;
Bauhofer, Adilson;
Cassocera, Marta;
Guimarães, Esperança Lourenço;
Abchande, Júlia Sambo;
Manhique-Coutinho, Lena;
Bero, Diocreciano;
Chissaque, Assucênio;
Munlela, Benilde;
Paulo Langa, José;
Cossa-Moiane, Idalécia;
Deus, Nilsa de.
Introdução: o Instituto Nacional de Saúde de Moçambique, implementou a Vigilância Nacional de Diarreias (ViNa
Dia) em 2014 cujo principal objectivo é determinar a carga de diarreias em crianças dos 0 aos 14 anos de idade,
e os agentes etiológicos associados, em quatro províncias de Moçambique....
Bactérias,
Enfermeiros,
Manutenção,
Medicina Preventiva,
Médicos,
Métodos,
Rotavirus,
Saúde,
Vírus,
Sistema Nacional de Vigilância em Saúde,
Criança,
Moçambique
Chissaque, Assucênio;
Bauhofer, Adilson Fernando Loforte;
Moiane, Idalécia Cossa;
Sitoe, Ezequias;
Munlela, Benilde;
Joao, Eva Dora;
Langa, Jerónimo Souzinho;
Chilaule, Jorfélia José;
Boene, Simone Salvador;
Cassocera, Marta;
Guimaraes, Esperança Lourenço;
Kellogg, Timothy;
Goncalves, Luzia;
Deus, Nilsa.
Globally, Rotavirus A (RVA) remains the leading cause of severe acute gastroenteritis associated with high childhood hospitalization and mortality, accounting for an estimated 128,515 deaths among children under five years old in 2016 [1, 2]. In Sub-Saharan Africa, RVA associated morbidity and mortality ...
d0000660,
d0123070,
d0222430,
Infecções,
d0090170,
d0005530,
d0146110,
Diarreia/prevenção & controle,
Rotavirus/genética,
Vacinas contra Rotavirus/administração & dosagem,
Infecções por Rotavirus,
Moçambique
Boane, Simone S;
João, Eva D;
Strydom, Amy;
Munlela, Benilde;
Chissaque, Assucênio;
Bauhofer, Adilson Fernando Loforte;
Nabetse, Elvino;
Dalilo, Latifo;
Cala, Aida;
Mapaco, Lourenço;
Chilaúle, Jorfélia;
O'Neill, Hester G;
Deus, nilza.
Rotavirus A (RVA) is an important pathogen causing gastroenteritis in many species, including humans and pigs. The objective of this study was to determine the prevalence of RVA in pigs from smallholdings and commercial farms in southern Mozambique and characterize the complete genomes of selected strain...
Introduction: Rotavirus A (RVA) is a leading cause of acute infant gastroenteritis in Mozambique, responsible for approximately 13,000 annual infant deaths in peri-urban and other areas. Aim: the present review aimed summarize the most relevant and recent literature regarding RVA infection in Mozambique....
Acácio, Sozinho;
Nhampossa, Tacilta;
Quintò, Llorenç;
Quintò, Llorenç;
Vubil, Delfino;
Garrine, Marcelino;
Bassat , Quique;
Farag, Tamer;
Panchalingam, Sandra;
Nataro, James P;
Kotloff , Karen L;
Levine, Myron M;
Tennant, Sharon M;
Alonso, Pedro L;
Mandomando, Inácio.
Rotavirus vaccines have been adopted in African countries since 2009, including Mozambique (2015). Disease burden data are needed to evaluate the impact of rotavirus vaccine. We report the burden of rotavirus-associated diarrhea in Mozambique from the Global Enteric Multicenter Study (GEMS) before vaccin...
Chissaque, Assucênio;
Cassocera, Marta;
Gasparinho, Carolina;
Langa, Jéronimo Souzinho;
Bauhofer, Adilson Fernando Loforte;
Chilaúle, Jorfélia José;
João, Eva Dora;
Munlela, Benilde António;
Sambo, Júlia Assiat Monteiro;
Boene, Simone Salvador;
Djedje, Marlene Bernardo;
Anapakala, Elda Muianga;
Guimarães, Esperança Lourenço;
Bero, Diocreciano Matias;
Manhique-Coutinho, Lena Vânia;
Cossa-Moiane, Idalécia;
Kellogg, Timothy A;
Augusta Pires Gonçalves, Luzia;
de Deus, Nilsa.
Background: Mozambique has a high burden of group A rotavirus (RVA) infection and chronic undernutrition. This
study aimed to determine the frequency and potential risk factors for RVA infection in undernourished children
under 5 years old with diarrhoea in Mozambique.
Methods: The analysis was conducted...
João, Eva D;
Munlela, Benilde;
Chissaque, Assucênio;
Chilaúle, Jorfélia;
Langa, Jerónimo;
Augusto, orvalho;
Boene, simone s;
Anapakala, elda;
Sambo, júlia;
Guimarães, esperança;
Bero, Diocreciano;
Cassocera, Marta;
Moiane, Idalécia Cossa;
Mwenda, Jason M;
Maurício, Isabel;
O’Neill, Hester G;
de Deus, Nilsa.
Group A rotavirus (RVA) remains the most important etiological agent associated with severe acute diarrhea in children. Rotarix® monovalent vaccine was introduced into Mozambique’s Expanded Program on Immunization in September 2015. In the present study, we report the diversity and prevalence of rotav...