Bulhoes, Elisio;
Farias, Carlos;
Florindo, Mayara;
Silva, Gustavo Fernandes da;
Holmvard, Oscar;
Silva, Ana Laura Soares;
Ferreira, Andre Carvalho;
Sales, Gabriel;
Schneider, Andre;
Roesch, Heveline Rayane Moura;
Guida, M Camila.
INTRODUCTION: Cancer therapy-induced cardiac dysfunction is a significant adverse effect of chemotherapeutic agents, particularly anthracyclines (ANT). High-potency statin therapy, such as atorvastatin, appears to exert a protective effect against this condition. OBJECTIVE: We aimed to perform a meta-ana...
BACKGROUND: Breast cancer (BC) is a significant global health issue, accounting for 1 in 8 cancer diagnoses worldwide. HLA class I molecules are typically expressed on the cell surface, but cancer cells can develop mechanisms to evade recognition by CTLs, including the downregulation of HLA class I expre...
Pivatto Júnior, Fernando;
Santos, Ângela Barreto Santiago;
Englert, Eduarda Foresti;
Mazzutti, Géris;
Costa, Guilherme Oliveira Magalhães;
Saffi, Marco Aurélio Lumertz;
Siebert, Marina;
Liedke, Pedro Emanuel Rubini;
Fritsch, Vinícius Henrique;
Biolo, Andreia.
BACKGROUND: The classic biomarkers troponin and brain natriuretic peptide (BNP), as well as the currently available risk scores, are far from being considered ideal for predicting cancer therapy-related cardiac dysfunction (CTRCD). MicroRNAs (miRNAs) are promising biomarkers for better identification of ...
Castro, Stellanny Cilene Rodrigues;
Souza, Dilma do Socorro Moraes de;
Gonçalves, Julle Kelle Pereira;
Sano, Vitor Kendi Tsuchiya;
Almeida, Artur Menegaz de;
Morbach, Victória;
Kelly, Francinny Alves;
Moraes, Francisco Cezar Aquino de;
Silva, Ana Laura Soares;
Silva, Barbara Lins;
Lobo, Artur de Oliveira Macena.
Breast Cancer (BC) is one of the most common cancers diagnosed in population femmale and it has several subtypes, one of them being theexpressing human epidermal growth factor receptor 2 positive (HER2 +), one of the treatments for HER2+ breast cancer consists of chemotherapy plus trastuzumab deruxtecan....
BACKGROUND: Contemporary understanding characterizes cardiotoxicity as a reduction in left ventricular ejection fraction (LVEF) by at least 10%, resulting in a final value below 53% in successive assessments. Nevertheless, breast cancer therapy can impact the cardiovascular system through various avenues...
BACKGROUND Breast cancer (BC) incidence is estimated to achieve over 3 million new cases and 1 million deaths by 2040. Beyond its physical toll, breast cancer detrimentally affects quality of life, imposing emotional, social, and financial burdens on patients and their families. Statins, commonly prescri...
Coelho, Verena Isabelle;
Chagas, Jaqueline Maria de Azevedo;
Costa, Fernando Henrique da Silva;
Azevedo, João Victor Bezerra de Moura;
Maciel, Kailane Luiza;
Mühlmann, Lindson;
China, Mayara Jéssica Monteiro;
Morais, Rainally Sabrina Freire de;
AMER, Shadya Teixeira;
Mendonça, Virgílio Dias Furtado;
Zanoni, Rodrigo Daniel.
A mastectomia preventiva relacionada às neoplasias de mama precoces é um
tema de grande importância na área da oncologia, especialmente para mulheres com alto risco genético de desenvolver câncer de mama. Objetivo: Descrever como a mastectomia relaciona-se com a prevenção de neoplasias de mama pr...
Resumo O câncer de mama é a neoplasia mais prevalente nas mulheres, em torno de 30% de todos os tipos de câncer, enquanto no sexo masculino é responsável por apenas 1% dos casos. No mundo, é a primeira causa de morte por câncer em mulheres. A incidência e a mortalidade variam de acordo com a etni...
Câncer é um conjunto de mais de 100 doenças, incluindo tumores malignos de diferentes locais, que possuem característica comum falha dos mecanismos que regulam o crescimento normal das células, proliferação e morte celular. O prognóstico do tumor pode ser de leve a grave, com invasão de tecidos ...
