BACKGROUND: Histopathological analysis of tissue samples is an ancillary complementary diagnostic tool in tuberculosis (TB) with variable sensitivity and specificity according to different clinical settings. We evaluated the spectrum of histological findings, their diagnostic sensitivity, diagnostic util...
Biopsia/métodos,
Chile,
Granuloma/diagnóstico,
Granuloma/microbiología,
Granuloma/patología,
Mycobacterium tuberculosis/genética,
Mycobacterium tuberculosis/aislamiento & purificación,
Estudios Retrospectivos,
Sensibilidad y Especificidad,
Tuberculosis/diagnóstico,
Tuberculosis/microbiología,
Tuberculosis/patología
Human tuberculosis is still a major world health concern. In Uruguay, contrary to the world trend, an increase in cases has been observed since 2006. Although the incidence of MDR-resistant strains is low and no cases of XDR-TB were registered, an increase in the number of patients with severe tuberculos...
ANTECEDENTES: El estado de Veracruz se ubica en el sureste de México y presenta una alta prevalencia de tuberculosis (TBC) y drogo resistencia. Sin embargo, la composición de los genotipos circulantes es poco conocida. OBJETIVO: Caracterizar la diversidad genética de la TBC en la jurisdicción sanitar...
Mycobacterium tuberculosis/genética,
Tuberculosis/microbiología,
Variación Genética,
Estudios Transversales,
México,
Genotipo,
Mycobacterium tuberculosis/aislamiento & purificación,
Mycobacterium tuberculosis/efectos de los fármacos,
Pruebas de Sensibilidad Microbiana,
Farmacorresistencia Bacteriana,
Tuberculosis/diagnóstico,
Técnicas de Tipificación Bacteriana/métodos
INTRODUCCIÓN: Tuberculosis (TBC) sigue siendo la segunda causa de muerte por una enfermedad infecto-contagiosa después del síndrome de inmunodeficiencia humana adquirida (SIDA). Actualmente, el escenario de técnicas y metodologías de laboratorio para la identificación y drogo-sensibilidad está cam...
Abstract Cutaneous tuberculosis is a rare infection that is difficult to diagnose, because it shows less sensitivity and specificity in classic complementary exams when compared with the pulmonary form. The Xpert MTB/RIF® method offers an early diagnosis that identifies the DNA of Mycobacterium tubercul...
ABSTRACT Multidrug-resistant tuberculosis (MDR-TB) represents a significant impact in transmission, outcome, and health costs. The World Health Organization recommends implementation of rapid diagnostic methods for multidrug-resistance detection. This study was performed to evaluate the frequency of pre-...
ABSTRACT OBJECTIVE To identify and synthesize the scientific knowledge produced regarding the effectiveness of the GeneXpert test in the diagnosis of pulmonary tuberculosis (TB) in people living with HIV/AIDS. METHODS Integrative literature review, which was searched on Embase, Scopus, PubMed, Cinahl...
Conceição, Emilyn Costa;
Salvato, Richard Steiner;
Gomes, Karen Machado;
Guimarães, Arthur Emil dos Santos;
da Conceição, Marília Lima;
Souza e Guimarães, Ricardo José de Paula;
Sharma, Abhinav;
Furlaneto, Ismari Perini;
Barcellos, Regina Bones;
Bollela, Valdes Roberto;
Anselmo, Lívia Maria Pala;
Sisco, Maria Carolina;
Niero, Cristina Viana;
Ferrazoli, Lucilaine;
Refrégier, Guislaine;
Lourenço, Maria Cristina da Silva;
Gomes, Harrison Magdinier;
de Brito, Artemir Coelho;
Catanho, Marcos;
Duarte, Rafael Silva;
Suffys, Philip Noel;
Lima, Karla Valéria Batista.
Molecular-typing can help in unraveling epidemiological scenarios and improvement for disease control strategies. A literature review of Mycobacterium tuberculosis transmission in Brazil through genotyping on 56 studies published from 1996-2019 was performed. The clustering rate for mycobacterial intersp...
Abstract INTRODUCTION: The intensification of research and innovation with the creation of networks of rapid and effective molecular tests as strategies for the end of tuberculosis are essential to avoid late diagnosis and for the eradication of the disease. We aimed to evaluate the cost-effectiveness ...
Hadi, S. A;
Kolte, I.V;
Brenner, E. P;
Cunha, E. A. T;
Simonsen, V;
Ferrazoli, L;
Villela, D. A. M;
Santos, R. S;
Ravi, J;
Sreevatsan, S;
Basta, & P. C.
After nearly a century of vaccination and six decades of drug therapy, tuberculosis (TB) kills more people annually than any other infectious disease. Substantial challenges to disease eradication remain among vulnerable and underserved populations. The Guarani-Kaiowá people are an indigenous population...
