Results: 142

What clinical, functional, and psychological factors before treatment are predictors of poor quality of life in cancer patients at the end of chemotherapy?

Summary Objective: To correlate physical activity level (PAL), functional capacity and psychological state with quality of life (QoL) in cancer patients undergoing chemotherapy (CT). Method: Observational cohort study. Patients (n=121) with any primary cancer site with indications of chemotherapy with ...

Vacunación en etapa de vigilancia en niños con cáncer

Salud pública Méx; 59 (5), 2017

Tumor del estroma gastrointestinal y trasplante renal
Gastrointestinal stromal tumor and renal transplant

Medicina (B.Aires); 77 (4), 2017
El tumor estromal gastrointestinal (GIST) representa alrededor del 1% de todos los tumores digestivos y su aparición en pacientes trasplantados renales es infrecuente. Aproximadamente el 95% muestra tinción positiva para c-kit/CD117. DOG1 es un anticuerpo recientemente descrito que se sobre-expresa en ...

Leucemia mieloide crónica: Monitoreo y factores predictivos de una respuesta favorable en el tratamiento con imatinib
Chronic myelogenous leukemia: monitoring and predictors of a favorable response to treatment with imatinib

Medicina (B.Aires); 77 (3), 2017
La supervivencia a cinco años de los pacientes con leucemia mieloide crónica en fase crónica tratados con inhibidores de tirosina quinasa es superior al 90%. Existen escasos datos a nivel local. Esta información puede ser de interés, ya que el imatinib genérico se encuentra disponible en la región...

Ethical issues on the "synthetic" phosphoethanolamine clinical trial

Summary Notwithstanding its approval by the National Committee for Ethics in Research (Conep) on April 19, 2016, a trial of the so-called "synthetic" phosphoethanolamine (syn-phospho) pill in cancer patients raises ethical concerns. An analysis by a laboratory contracted by the Ministry of Science, Techn...

Adjuvant treatment or primary topical monotherapy for ocular surface squamous neoplasia: a systematic review

Arq. bras. oftalmol; 80 (2), 2017
ABSTRACT In this systematic review, we evaluated studies involving adjuvant and primary topical treatment for ocular surface squamous neoplasia (OSSN). The findings were: (i) adjuvant 5-fluorouracil (5-FU) reduces the risk of relapse after surgical excision with mild side effects [level Ib, grade of reco...

Combination of TACE and Sorafenib Improves Outcomes in BCLC Stages B/C of Hepatocellular Carcinoma: A Single Centre Experience

Ann. hepatol; 16 (2), 2017
ABSTRACT Background & Aim. Transarterial chemoembolization (TACE) or sorafenib is recommended for hepatocellular carcinoma BCLC stages B and C respectively. We studied the role of combination of TACE and sorafenib in BCLC stages B/C. Material and methods. We undertook an observational study on a ...

Practical Considerations of Real Life of Hepatocellular Carcinoma in a Tertiary Center of Brazil

Ann. hepatol; 16 (2), 2017
ABSTRACT Background. Hepatocellular carcinoma (HCC) is the most common malignancy that develops in cirrhotic livers. Its clinical and epidemiological characteristics and mortality rates vary according to geographical region. The objective of this study was to evaluate the clinical profile, epidemiologi...

Periungual tegumentary leishmaniasis: a diagnostic challenge

An. bras. dermatol; 92 (2), 2017
Abstract: Periungual and paronychia-like skin lesions can mimic various diseases, setting up a diagnostic challenge that invariably requires correlation with complementary tests. We report a case of an ulcerated tumor of the nailfold diagnosed as leishmaniasis. Although paronychia-like cutaneous leishman...

Melanoma: tumor microenvironment and new treatments

An. bras. dermatol; 92 (2), 2017
Abstract: In the recent past years, many discoveries in the tumor microenvironment have led to changes in the management of melanoma and it is rising up hopes, specially, to those in advanced stages. FDA approved seven new drugs from 2011 to 2014. They are: Vemurafenib, Dabrafenib and Trametinib, kinases...