Results: 1422

Platelet-derived growth factor A mRNA in platelets is associated with the degree of hepatic fibrosis in chronic hepatitis C

Abstract: INTRODUCTION: Transforming growth factor beta 1 (TGFB1) and platelet-derived growth factor (PDGF) are the main cytokines related to hepatic fibrogenesis. METHODS: RNA isolated from the platelets and hepatic tissue of 43 HCV carriers was used for quantitative polymerase chain reaction to det...

Colpopexia al ligamento sacroespinoso con CapioTM; cirugía, resultados y evolución de pacientes
Sacroespinous ligament colpopexy with CapioTM; surgery patient outcomes and evolution

Introducción: El prolapso genital femenino altera significativamente la calidad de vida de la mujer. El prolapso apical es el segundo más frecuente después del defecto de pared anterior y la colposuspensión al ligamento sacroespinoso es una de las técnicas quirúrgicas descritas para su tratamiento....

Manejo anestesiológico de pacientes con trastorno hipertensivo del embarazo
Anesthesiological management of patients with hypertensive disorder of pregnancy

Los Trastornos hipertensivos del embarazo (THE) contribuyen a la morbimortalidad materna y fetal. En Chile sigue siendo la 2ª causa de muerte materna. Las Sociedades Estadounidense (ACOG) y Canadiense (SOGC) de Ginecología y Obstetricia publicaron una actualización de sus guías de hipertensión en el...

Diagnóstico y manejo de colitis ulcerosa grave: una mirada actualizada

Rev. méd. Chile; 145 (1), 2017
Ulcerative Colitis (UC) is a chronic inflammatory disease involving the colon, with alternating periods of remission and activity. Exacerbations can be severe and associated with complications and mortality. Diagnosis of severe UC is based on clinical, biochemical and endoscopic variables. Patients with ...

Comparative Study between Perfusion Changes and Positive Findings on Coronary Flow Reserve

Arq. bras. cardiol; 108 (1), 2017
Abstract Background: Functional assessment of coronary artery obstruction is used in cardiology practice to correlate anatomic obstructions with flow decrease. Among such assessments, the study of the coronary fractional flow reserve (FFR) has become the most widely used. Objective: To evaluate the cor...

Pain-induced depression is related to overestimation of sleep quality in a very elderly population with pain

Arq. neuropsiquiatr; 75 (1), 2017
ABSTRACT Objective: To study the quality of sleep in very elderly people with chronic pain. Methods: We investigated 51 very elderly people without dementia and with chronic pain according to the Geriatric Pain Measure. Katz and Lawton questionnaires were used to evaluate functionality. The Geriatric D...

MacArthur Competence Assessment Tool for Treatment in Alzheimer disease: cross-cultural adaptation

Arq. neuropsiquiatr; 75 (1), 2017
ABSTRACT Objective: We adapted the MacArthur Competence Assessment Tool for Treatment (MacCAT-T) to Brazilian Portuguese, pilot testing it on mild and moderate patients with Alzheimer's disease (AD). Methods: The cross-cultural process required six steps. Sixty-six patients with AD were assessed for co...

Compound Heterozygous SCN5A Mutations in a Toddler - Are they Associated with a More Severe Phenotype?

Arq. bras. cardiol; 108 (1), 2017
Abstract Compound heterozygosity has been described in inherited arrhythmias, and usually associated with a more severe phenotype. Reports of this occurrence in Brugada syndrome patients are still rare. We report a study of genotype-phenotype correlation after the identification of new variants by geneti...

Severe microscopic polyangiitis with unilateral vocal cord paralysis as initial manifestation

Colomb. med; 48 (1), 2017
Abstract Case Description: A 16 year-old female who presented with initial ear, nose and throat manifestations who later progressed to severe renal disease, requiring hemodialysis after 11 months of unique laryngeal involvement. Clinical Findings: Unilateral vocal cord paralysis without other symptom...

The effectiveness of heparin, platelet-rich plasma (PRP), and silver nanoparticles on prevention of postoperative peritoneal adhesion formation in rats

Acta cir. bras; 32 (1), 2017
Abstract Purpose: To assess the effectiveness of heparin, platelet-rich plasma (PRP), and silver nanoparticles on prevention of postoperative adhesion in animal models. Methods: Sixty males Albino Wistar rats aged 5 to 6 weeks were classified into five groups receiving none, heparin, PRP, silver nanopa...