ABSTRACT Background: The emergence of antibiotic resistance is increasing and there are few effective antibiotics to treat infections caused by resistant and multidrug resistant bacterial pathogens. This study aimed to evaluate the in vitro activity of ceftolozane-tazobactam against clinical bacterial i...
Background: The main objective of this study was to isolate fungi associated with Anthopleura xanthogrammica and measure their antimicrobial and enzymatic activities. A total of 93 fungal strains associated with A. xanthogrammica were isolated in this study, of which 32 isolates were identified using bot...
Anémonas de Mar/microbiologÃa,
Biodiversidad,
Aspergillus/aislamiento & purificación,
Aspergillus/enzimologÃa,
Antibacterianos/aislamiento & purificación,
Antibacterianos/farmacologÃa,
Poligalacturonasa/metabolismo,
Amilasas/metabolismo,
Péptido Hidrolasas/metabolismo,
Bacterias/efectos de los fármacos,
ADN Espaciador Ribosómico,
Hongos/aislamiento & purificación,
Aspergillus/genética,
Hongos/genética,
Filogenia
Objective: To evaluate the cost-effectiveness of ceftolozane/tazobactam + metronidazole (C/T+M) and ceftolozane/tazobactam (C/T) compared with 8 alternatives used in the treatment of complicated intraabdominal infection (cIAI) and complicated urinary tract infection (cUTI) respectively. Methods: A Mon...
Resumen Introducción: Staphylococcus aureus es uno de los patógenos con mayor prevalencia en el mundo, asociado a una alta tasa de mortalidad y un rápido desarrollo de resistencia a los antimicrobianos. A pesar de su patogenicidad, su seguimiento epidemiológico en México es escaso. Objetivo: Anali...
Staphylococcus aureus Resistente a Meticilina/clasificación,
Staphylococcus aureus Resistente a Meticilina/efectos de los fármacos,
Staphylococcus aureus Resistente a Meticilina/genética,
Infecciones Estafilocócicas/epidemiologÃa,
Infecciones Estafilocócicas/microbiologÃa,
Antibacterianos/farmacologÃa,
Estudios Transversales,
Genotipo,
México/epidemiologÃa,
Pruebas de Sensibilidad Microbiana,
Prevalencia,
Estudios Prospectivos,
Factores de Virulencia/genética
Resumen Utilizando cepas clÃnicas de bacilos gramnegativos multi-resistentes (MDR), comparamos las CIM obtenidas de la microdilución en caldo, el método de referencia y el método de elución de sensidiscos. Encontramos que, con la excepción de A. baumannii, los resultados fueron muy similares. El mÃ...
Abstract INTRODUCTION: Pseudomonas aeruginosa is an opportunistic pathogen associated with healthcare-related infections, affecting mainly patients with underlying diseases and immunosuppression. This microorganism has several virulence mechanisms that favour its pathogenesis, including the production o...
Abstract INTRODUCTION: Methicillin-resistant Staphylococcus aureus (MRSA) is a common pathogen causing healthcare-associated infections. Owing to the restricted use of beta-lactams in MRSA infections, non-beta-lactam antimicrobials are required for treatment. However, MRSA can develop resistance mechan...
Abstract INTRODUCTION: The present study aimed to determine the incidence of health care-associated infections (HCAIs) and identify the main resistant microorganisms in intensive care unit (ICU) patients in a Brazilian university hospital. METHODS: A retrospective cohort study was conducted in a Brazi...
Antibacterianos/farmacologÃa,
Bacteriemia/microbiologÃa,
Bacteriemia/mortalidad,
Farmacorresistencia Bacteriana,
Bacterias Gramnegativas/clasificación,
Bacterias Gramnegativas/efectos de los fármacos,
Bacterias Gramnegativas/aislamiento & purificación,
Bacterias Grampositivas/clasificación,
Bacterias Grampositivas/efectos de los fármacos,
Bacterias Grampositivas/aislamiento & purificación,
Mortalidad Hospitalaria,
Incidencia,
Unidades de Cuidados Intensivos,
Pruebas de Sensibilidad Microbiana,
Persona de Mediana Edad,
Estudios Retrospectivos,
Factores de Tiempo
Abstract INTRODUCTION Antibiotic resistance in carbapenemase-producing Klebsiella pneumoniae is acquired and disseminated mainly by plasmids. Therefore, we aimed to investigate the occurrence of carbapenemase genes, analyze the genetic diversity by ERIC-PCR, and examine the most common plasmid incompat...
Abstract INTRODUCTION: This study investigated the genetic environment of bla KPC-2 in Klebsiella pnemoniae multi-drug resistant clinical isolates. METHODS: Four carbapenemase gene isolates resistant to carbapenems, collected from infected patients from two hospitals in Brazil, were investigated using...
Antibacterianos/farmacologÃa,
ADN Bacteriano/genética,
Farmacorresistencia Bacteriana Múltiple,
Infecciones por Klebsiella/microbiologÃa,
Klebsiella pneumoniae/enzimologÃa,
Klebsiella pneumoniae/genética,
Klebsiella pneumoniae/aislamiento & purificación,
Pruebas de Sensibilidad Microbiana,
Plásmidos/genética,
Reacción en Cadena de la Polimerasa,
beta-Lactamasas/genética